Impact of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific Antigen

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Chicago
Study ID
NCT05512754
Phase
PHASE4
Status
Recruiting
Apply to this trial

Conditions

  • Elevated Serum PSA

Eligibility Criteria

Sex
MALE
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Ibuprofen 400 mg — DRUG
    400 mg tablet

Study Details

The purpose of this study is to assess the impact of ibuprofen in men with elevated serum PSA.

Key Dates

Start date
Aug 1, 2022
Status verified
Dec 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
200 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Ibuprofen
    Participants receive Ibuprofen 400 mg tablet orally every 8 hours for 10 days
  • No Intervention: Control
    Participants receive no NSAIDs

Primary Outcome Measure

Change of serum PSA compared with baseline [ Time Frame: Baseline, 6 weeks ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
University of ChicagoChicagoIllinois60637
Scott Eggener, MD
[email protected]
773-834-5087
Leila Yazdanbakhsh, MSCI
[email protected]
7738345087
Scott Eggener, MD (PRINCIPAL_INVESTIGATOR)
Albany Medical CollegeAlbanyNew York12208
Badar Mian, MD
[email protected]
518-262-8579
Brenda Romeo
[email protected]
Badar Mian, MD (PRINCIPAL_INVESTIGATOR)
The Pennsylvania State University at The Milton S. Hershey Medical CenterHersheyPennsylvania17033
Jay Raman, MD
[email protected]
717-531-8848
Dennis Head
[email protected]
Jay Raman, MD (PRINCIPAL_INVESTIGATOR)

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