Clinical Trials at Rush University Medical Center

As of June 2026, 165 paid clinical trials are recruiting at Rush University Medical Center, located at 1725 W HARRISON ST, NUMBER 1118 UNIVERSITY NEUROLOGISTS, CHICAGO, IL 60612-3841, phone (312) 942-5936 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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165 clinical trials at Rush University Medical Center

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Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery

for Anterior Cruciate Ligament Reconstruction

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT07020312·Phase 2·Recruiting

Apply to this trial

FiberLocker® System Augmentation of Rotator Cuff Repairs

for Rotator Cuff Tear

4 locations incl. Chicago

Sponsor: ZuriMED Technologies Inc.

Sex: All·Age: 30 - 70

Code: NCT06918041·Recruiting

Apply to this trial

Biomarkers for Cognitive Decline in Intracerebral Hemorrhage

for Primary Intracerebral Hemorrhage

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 80

Code: NCT06836141·Recruiting

Apply to this trial

Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

for Obstructive Sleep Apnea (OSA)

5 locations incl. Colorado Springs

Sponsor: Inspire Medical Systems, Inc.

Sex: All·Age: 18+

Code: NCT07113288·Recruiting

Apply to this trial

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

for Adjustment Disorder

30 locations incl. Birmingham

Sponsor: Reunion Neuroscience Inc

Sex: All·Age: 18 - 80

Code: NCT07002034·Phase 2·Recruiting

Apply to this trial

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

for Relapsing Multiple Sclerosis

Drug: Remibrutinib

38 locations incl. Scottsdale

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 40 - 70

Code: NCT06846281·Phase 3·Recruiting

Apply to this trial

Comparing Single-Session Therapies for Chronic Pain

for Chronic Musculoskeletal Pain

2 locations incl. Chicago

Sponsor: Mark A. Lumley

Sex: All·Age: 18+

Code: NCT07008105·Recruiting

Apply to this trial

The Use of CCK vs PS in Revision TKAs

for Aseptic Loosening of Prosthetic Joint

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06782295·Phase 4·Recruiting

Apply to this trial

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

for Ulcerative Colitis

Drug: Tirzepatide

37 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937086·Phase 3·Recruiting

Apply to this trial

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

for Crohn's Disease

Drug: Tirzepatide

35 locations incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937099·Phase 3·Recruiting

Apply to this trial

REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

for Angelman Syndrome

15 locations incl. Los Angeles

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 50

Code: NCT06914609·Phase 3·Recruiting

Apply to this trial

Automatic Tube Compensation vs. Pressure Support Ventilation During Spontaneous Breathing Trials in Adults

for Spontaneous Breathing Trial in ICU

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT07005505·Recruiting

Apply to this trial

Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

for Cervical Cancer

92 locations incl. Phoenix

Sponsor: Pfizer

Sex: Female·Age: 18+

Code: NCT06952660·Phase 4·Recruiting

Apply to this trial

Preoperative Fasting vs. Not Fasting in Critically Ill Patients

for Critical Illness

19 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06751043·Recruiting

Apply to this trial

Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

for Acute Respiratory Failure

9 locations incl. Chicago

Sponsor: Brian Driver

Sex: All·Age: 18+

Code: NCT06934876·Recruiting

Apply to this trial

Preventative Screening and Health Coaching in a Food Insecure Population

for Cardiovascular Disease Prevention

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 40 - 75

Code: NCT06907524·Not Yet Recruiting

The Dragon PLC Trial (DRAGON-PLC)

for Primary Liver Cancer

5 locations incl. New Haven

Sponsor: Maastricht University

Sex: All·Age: 18+

Code: NCT06914648·Recruiting

Apply to this trial

The Pivotal Study of RapidPulseTM Aspiration System

for Acute Ischemic Stroke

18 locations incl. Torrance

Sponsor: RapidPulse, Inc

Sex: All·Age: 18 - 80

Code: NCT06029491·Recruiting

Apply to this trial

Randomized Control Trial of Sleeve Gastrectomy With Tirzepatide in Maximizing Weight Loss

for Obesity and Obesity-related Medical Conditions

Drug: Tirzepatide

1 location in Chicago

Sponsor: Nicholas Skertich

Sex: All·Age: 18 - 65

Code: NCT06734273·EARLY_Phase 1·Recruiting

Apply to this trial

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

for Mantle Cell Lymphoma

Drug: Sonrotoclax

37 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06742996·Phase 3·Recruiting

Apply to this trial

Validating Innovative Biosensors for Rett Autonomic Symptom Tracking

for Rett Syndrome

3 locations incl. Chicago

Sponsor: Rett Syndrome Research Trust

Sex: All·Age: All ages

Code: NCT06338267·Recruiting

Apply to this trial

Exalt Single-use Duodenoscope Vs Reusable Scope, a Randomized Controlled Trial

for Biliary Diseases

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 19+

Code: NCT06895785·Recruiting

Apply to this trial

MOTION Clinical Trial

for Osteoarthritis, Knee

8 locations incl. Davis

Sponsor: Moximed

Sex: All·Age: All ages

Code: NCT06843980·Recruiting

Apply to this trial

KRONOS Versus Breg T-Scope Post-operative Knee Braces Following Anterior Cruciate Ligament (ACL) Reconstruction

for Anterior Cruciate Ligament (ACL) Reconstruction Surgery

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT07090616·Recruiting

Apply to this trial

E3 Hypertension - A Team-based, Multidisciplinary Model in Addressing Barriers to Hypertension Control

for Hypertension

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06899750·Recruiting

Apply to this trial

Erector Spinae Plane Block for Acute Back Pain in the Emergency Department

for Low Back Pain

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06745453·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

for NonSegmental Vitiligo

Drug: Ruxolitinib

80 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 2 - 11

Code: NCT06548360·Phase 3·Recruiting

Apply to this trial

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

23 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting

Apply to this trial

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

for Coronavirus Disease (COVID-19)

71 locations incl. Cullman

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06667700·Phase 3·Recruiting

Apply to this trial

End Diagnostic Overshadowing:Addressing Ableism in Diagnoses

for Disabilities Multiple

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 3 - 89·Accepts healthy volunteers

Code: NCT06608758·Recruiting

Apply to this trial

Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy

for Ventricular Tachycardia

5 locations incl. Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06138873·Recruiting

Apply to this trial

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

for Liver Neoplasms

30 locations incl. Fullerton

Sponsor: HistoSonics, Inc.

Sex: All·Age: 22+

Code: NCT06486454·Recruiting

Apply to this trial

iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure

for Heart Failure

2 locations incl. Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT06205225·Recruiting

Apply to this trial

(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain

for Pain, Neuropathic

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 75

Code: NCT05864053·Phase 1, Phase 2·Recruiting

Apply to this trial

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

for Colitis, Ulcerative

22 locations incl. Mesa

Sponsor: Pfizer

Sex: All·Age: 18 - 64

Code: NCT06398626·Recruiting

Apply to this trial

Optimal Timing for Spontaneous Breathing Trials

for Respiration, Artificial

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 21+

Code: NCT06561295·Recruiting

Apply to this trial

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for Treatment Resistant Depression

24 locations incl. Birmingham

Sponsor: Abbott Medical Devices

Sex: All·Age: 22 - 70

Code: NCT06423430·Recruiting

Apply to this trial

Activity and Recreation in Communities for Health

for Depression

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06093282·Enrolling By Invitation

Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)

for Pulmonary Embolism

10 locations incl. Irvine

Sponsor: Innova Vascular, Inc.

Sex: All·Age: 18 - 85

Code: NCT06041594·Recruiting

Apply to this trial

Long-term Extension of GTX-102 in Angelman Syndrome

for Angelman Syndrome

6 locations incl. Los Angeles

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: All ages

Code: NCT06415344·Phase 3·Enrolling By Invitation