Endocrinology Clinical Trials in Chicago, IL

As of June 2026, 70 paid clinical trials are recruiting for Endocrinology in Chicago, Illinois. Endocrinology trials investigate next-generation GLP-1 and GIP agonists, novel insulin formulations, beta-cell replacement therapies, and metabolic interventions across diabetes, obesity, and thyroid disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

70 clinical trials for Endocrinology

·Clear filters·↓ Download CSV

Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors

for Obesity

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT05687604·Recruiting

Apply to this trial

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

for Chronic Obstructive Pulmonary Disease

5 locations incl. Boise

Sponsor: Seattle Institute for Biomedical and Clinical Research

Sex: All·Age: 18+

Code: NCT06390345·Recruiting

Apply to this trial

A Hybrid Effectiveness-implementation Trial to Reduce Diabetes Distress in Teenagers

for Type 1 Diabetes Mellitus

1 location in Chicago

Sponsor: Jill Weissberg-Benchell, Ph.D.

Sex: All·Age: 14 - 18

Code: NCT06709755·Recruiting

Apply to this trial

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

for Obesity

Drug: Tirzepatide

15 locations incl. Los Angeles

Sponsor: Eli Lilly and Company

Sex: All·Age: 12 - 17

Code: NCT06439277·Phase 3·Recruiting

Apply to this trial

RemI for Post-Bariatric Surgery Weight Regain

for Obesity

2 locations incl. Chicago

Sponsor: Temple University

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06292936·Recruiting

Apply to this trial

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for Diabetes Mellitus, Type 2

124 locations incl. Chandler

Sponsor: Cleerly, Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06112418·Recruiting

Apply to this trial

Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)

for Type 1 Diabetes Mellitus

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 65

Code: NCT06305286·Phase 1, Phase 2·Recruiting

Apply to this trial

Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

for Diabetes

21 locations incl. Dothan

Sponsor: Sonavex, Inc.

Sex: All·Age: 18 - 84

Code: NCT06190717·Recruiting

Apply to this trial

Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors

for Hypertension

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: Female·Age: 18 - 99

Code: NCT06504914·Recruiting

Apply to this trial

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

for Obesity

49 locations incl. Chandler

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT06143956·Phase 2·Recruiting

Apply to this trial

Predictors of Behavioral Obesity Treatment Outcomes

for Obesity

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05326477·Recruiting

Apply to this trial

TArgeting Type 1 Diabetes Using POLyamines (TADPOL)

for Type 1 Diabetes

7 locations incl. Aurora

Sponsor: Emily K. Sims

Sex: All·Age: 4 - 40

Code: NCT05594563·Phase 2·Recruiting

Apply to this trial

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

for Diabetes

27 locations incl. Phoenix

Sponsor: Marinella Temprosa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05704309·Enrolling By Invitation

Better Lifestyle Counseling for African American Women During Pregnancy

for Overweight or Obesity

2 locations incl. Chicago

Sponsor: University of Illinois at Chicago

Sex: Female·Age: 18 - 40

Code: NCT05234125·Recruiting

Apply to this trial

Multivariable Artificial Pancreas: Detecting and Mitigating Unannounced Physical Activity and Acute Psychological Stress

for Type 1 Diabetes

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 20 - 60

Code: NCT05145374·Recruiting

Apply to this trial

Role of Adiposomes in Endothelial Dysfunction

for Obesity

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18 - 50

Code: NCT05199454·Recruiting

Apply to this trial

Promoting Preconception Care and Diabetes Self-Management Among Reproductive-Aged Women With Diabetes

for Diabetes Mellitus, Type 2

1 location in Chicago

Sponsor: Northwestern University

Sex: Female·Age: 18 - 44

Code: NCT04976881·Recruiting

Apply to this trial

Improvement of Hyperglycemia/Diabetes in Patients to Improve Safety

for Diabetes Mellitus, Type 2

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06096311·Recruiting

Apply to this trial

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

for B-cell Acute Lymphoblastic Leukemia

20 locations incl. Los Angeles

Sponsor: Etan Orgel

Sex: All·Age: 10 - 25

Code: NCT05082519·Phase 2·Recruiting

Apply to this trial

Diabetic Neuropathy in Spinal Cord Stimulator Patients

for Diabetes Mellitus

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT04687215·Recruiting

Apply to this trial

My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes

for Type 2 Diabetes

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT05208164·Recruiting

Apply to this trial

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

for Diabetes Mellitus, Type 1

12 locations incl. Duarte

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT04786262·Phase 3·Recruiting

Apply to this trial

Sleep, Diabetic Retinopathy and Melatonin

for Diabetes Mellitus

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 40 - 65

Code: NCT04547439·Phase 2·Recruiting

Apply to this trial

Rare and Atypical Diabetes Network

for Diabetes Mellitus

13 locations incl. Aurora

Sponsor: University of South Florida

Sex: All·Age: All ages

Code: NCT05544266·Recruiting

Apply to this trial

Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss

for Peripheral Artery Disease

7 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT04228978·Recruiting

Apply to this trial

DNA Methylation and Vascular Function

for Obesity

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT03527420·Recruiting

Apply to this trial

Kidney Precision Medicine Project

for Acute Kidney Failure

13 locations incl. Tucson

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04334707·Recruiting

Apply to this trial

Multicenter Assessment of the Pancreas in Type 1 Diabetes

for Diabetes Mellitus

4 locations incl. Aurora

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 8+·Accepts healthy volunteers

Code: NCT03585153·Enrolling By Invitation

Islet Transplantation in Patients With "Brittle" Type I Diabetes

for Diabetes Mellitus, Type 1

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 70

Code: NCT01630850·Recruiting

Apply to this trial

Islet Transplantation in Type 1 Diabetic Kidney Allograft

for Diabetes Mellitus, Type 1

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 68

Code: NCT01241864·Phase 2·Recruiting

Apply to this trial

Conditions in Endocrinology (Chicago, IL)

Obesity / overweight· 30 Type 1 diabetes· 16 Type 2 diabetes· 13 Diabetes (general / unspecified)· 10 Metabolic syndrome· 5 Prediabetes· 3 Insulin resistance· 1