Multicenter Assessment of the Pancreas in Type 1 Diabetes

Part of paid clinical trials in Aurora, Colorado.

Sponsor
Vanderbilt University Medical Center
Study ID
NCT03585153
Status
Enrolling By Invitation

Conditions

  • Diabetes Mellitus

Eligibility Criteria

Sex
ALL
Age
8 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Non-contrast magnetic resonance imaging — OTHER
    subjects lie in an MRI machine (non-contrast) for 30 minutes while we take pictures of their pancreas

Study Details

The overall goal of this research is to develop and validate standard operating procedures (SOP) to assess the human pancreas in individuals with type 1 diabetes (T1D) and other forms of diabetes using advanced, quantitative magnetic resonance imaging (MRI) approaches.

Key Dates

Start date
Feb 19, 2014
Status verified
Oct 2025
Primary completion
Dec 31, 2028
Completion
Dec 31, 2050

Study Design

Enrollment
250 participants (estimated)

Arms

  • Arm: Individuals with stage 3 T1D
    Individuals with overt stage 3 type 1 diabetes
  • Arm: Healthy control
    Individuals without type 1 diabetes
  • Arm: Autoantibody positive
    Individuals with early stage type 1 diabetes (stage 1, stage 2) who possess two or more type 1 diabetes-related autoantibodies
  • Arm: Monogenic diabetes
    Individuals with monogenic diabetes

Primary Outcome Measure

Pancreas Volume Index [ Time Frame: up to 10 years ]

Locations (4)

FacilityCityStateZIPSite coordinators
University of Colorado, Barbara Davis CenterAuroraColorado80045-
University of Chicago, Kovler Diabetes CenterChicagoIllinois60637-
Vanderbilt University Medical CenterNashvilleTennessee37232-
University of Texas at Austin, Dell Medical SchoolAustinTexas78712-

Find similar trials in Aurora, CO

By research site
University of Colorado, Barbara Davis Center· Aurora, COUniversity of Chicago, Kovler Diabetes Center· Chicago, ILVanderbilt University Medical Center· Nashville, TNUniversity of Texas at Austin, Dell Medical School· Austin, TX

Related Studies