Paid Clinical Trials in California

California has 6,497 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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6,497 clinical trials

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A Study to Evaluate the Effect of Food on the Bioavailability of AJ201, and Safety, Tolerability, and Pharmacokinetics of AJ201 in Japanese and White Healthy Male Participants

for Healthy Male Adults

1 location in Los Alamitos

Sponsor: AnnJi Pharmaceutical Co., Ltd.

Sex: Male·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07549919·Phase 1·Recruiting

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Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

for Lung Non-Small Cell Carcinoma

13 locations incl. Goodyear

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07288034·Phase 2·Recruiting

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Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

for Ewing Sarcoma

4 locations incl. Los Angeles

Sponsor: Amgen

Sex: All·Age: 2+

Code: NCT07297979·Phase 1·Recruiting

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Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)

for Atrial Fibrillation (AF)

22 locations incl. Birmingham

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT07298473·Recruiting

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AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

for Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)

5 locations incl. Irvine

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07403721·Phase 1·Recruiting

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Accurate Point of Care Liver Disease Diagnostics (Phase 2)

for MASLD

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT07518784·Recruiting

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Engaging Mental Effort: Process- and Person-Based Reward Experiences, Effort Reinforcement Intervention, and Cascading Effects on Challenging Tasks

for Performance vs. Effort Rewards

1 location in Davis

Sponsor: University of California, Davis

Sex: All·Age: 9 - 13·Accepts healthy volunteers

Code: NCT07557732·Recruiting

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A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively

for Schizophrenia

Drug: KarXT

19 locations incl. Anaheim

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 5 - 17

Code: NCT07424404·Phase 3·Recruiting

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A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation

for Advanced/Metastatic Colorectal Adenocarcinoma

Drug: BAY 3771249

7 locations incl. Phoenix

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT07535112·Phase 1·Recruiting

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Phase 1 Study of C.001 in Retinal Degeneration

for Geographic Atrophy

1 location in Beverly Hills

Sponsor: Cellio Therapeutics Inc

Sex: All·Age: 18+

Code: NCT07594236·Phase 1·Recruiting

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Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

for Huntington Disease

1 location in Irvine

Sponsor: Leslie Thompson

Sex: All·Age: 18 - 65

Code: NCT07451613·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1

for Narcolepsy Type 1

Drug: ALKS 2680

15 locations incl. Los Angeles

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT07455383·Phase 3·Recruiting

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Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity

for Obesity

19 locations incl. Chandler

Sponsor: Kailera

Sex: All·Age: 18 - 75

Code: NCT07497880·Phase 2·Recruiting

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Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers

for Pharmacokinetics

1 location in Chula Vista

Sponsor: Amphastar Pharmaceuticals, Inc.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07560150·Phase 2, Phase 3·Recruiting

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Human Laboratory Study of Apremilast for Alcohol Use Disorder

for Alcohol Use Disorder

3 locations incl. Los Angeles

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 21+

Code: NCT07325266·Phase 2·Recruiting

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Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable

for Atrial Fibrillation (AF)

13 locations incl. Dothan

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07430956·Phase 3·Recruiting

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Vevye + Flarex Combination Therapy for Dry Eye

for Dry Eye

1 location in Azusa

Sponsor: Canyon City Eyecare

Sex: All·Age: 18+

Code: NCT07553455·Phase 4·Enrolling By Invitation

Diagnostic Refinement and Educational Approaches in Managing Bone Marrow Transplantation

for GVHD

1 location in San Diego

Sponsor: Scripps Health

Sex: All·Age: 18+

Code: NCT06590285·Recruiting

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Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)

for Hereditary Angioedema (HAE)

15 locations incl. Litchfield Park

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07428499·Phase 3·Recruiting

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An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)

for Post Traumatic Stress Disorder

26 locations incl. Little Rock

Sponsor: Transcend Therapeutics

Sex: All·Age: 18+

Code: NCT07456696·Phase 3·Recruiting

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Hypoxia and Hemodilution Testing in Healthy Adult Volunteers

for Hypoxia

1 location in San Francisco

Sponsor: Nihon Kohden

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT07503171·Not Yet Recruiting

A Study to Evaluate the Pharmacokinetics and Safety of XEMBIFY Versus Gamunex-C in Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

for CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy)

5 locations incl. Rancho Mirage

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18+

Code: NCT07540221·Phase 3·Recruiting

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Biomolecular Characteristics of Reminder-Focused Positive-Psychiatry

for Posttraumatic Stress Disorder

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 11 - 15

Code: NCT04529031·Recruiting

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A Trial of Baricitinib in Patients With Cardiac Sarcoidosis

for Cardiac Sarcoidosis

Drug: Baricitinib

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18 - 85

Code: NCT06868381·Phase 2·Not Yet Recruiting

A Study Evaluating the Safety and Tolerability of Artesunate in Patients With Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension (PAH)

1 location in Stanford

Sponsor: Joseph C. Wu

Sex: All·Age: 18 - 60

Code: NCT06872112·Phase 1·Recruiting

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A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

for Knee Osteoarthritis

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 50 - 95

Code: NCT06906939·EARLY_Phase 1·Recruiting

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Effect of Watermelon on Cardiometabolic Health

for Cardiometabolic Health Indicators

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT07006636·Not Yet Recruiting

Improving Cognitive Rehabilitation Outcomes

for Mild Traumatic Brain Injury

2 locations incl. San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07055633·Recruiting

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Initial Study Sesting Efficacy and Tolerability of PT150 for PTSD in Veterans

for PTSD - Post Traumatic Stress Disorder

2 locations incl. San Diego

Sponsor: San Diego Veterans Healthcare System

Sex: All·Age: 18 - 65

Code: NCT07187011·Phase 2·Not Yet Recruiting

Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI

for Mild to Moderate Traumatic Brain Injury

1 location in Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 65

Code: NCT07190365·Recruiting

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Exercise and Mortality in Middle-Aged and Older Adults

for Overall Survival (All-cause Mortality)

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 55 - 74

Code: NCT07224659·Not Yet Recruiting

The TRIBECA Study (TRIessence/Byqlovi for Easier CAtaract Surgery)

for Post Cataract Surgery

1 location in Laguna Hills

Sponsor: Research Insight LLC

Sex: All·Age: 22+

Code: NCT07276802·Phase 4·Not Yet Recruiting

Precise Cooler for Donor Heart Transport

for Heart Transplantation

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: All ages

Code: NCT07354763·Not Yet Recruiting

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

for Systematic Lupus Erythematosus

Drug: Enpatoran

4 locations incl. Upland

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: 18 - 75

Code: NCT07355218·Phase 3·Recruiting

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A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study)

for Type-2 Diabetes Mellitus

4 locations incl. Scottsdale

Sponsor: Aqua Medical, Inc.

Sex: All·Age: 22 - 65

Code: NCT07355270·Recruiting

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Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults

for Sickle Cell Disease

1 location in Torrance

Sponsor: Mohsen Saidinejad

Sex: All·Age: 5 - 20

Code: NCT07369024·Phase 2·Recruiting

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A First-in-Patient Study to Evaluate the Safety and Tolerability of HB-2121 as a Diagnostic for Celiac Disease

for Celiac Disease

1 location in Palo Alto

Sponsor: Nielsen Fernandez-Becker

Sex: All·Age: 18+

Code: NCT07377565·Phase 1·Recruiting

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Bowel Continence Across the Lifespan in People With Spina Bifida

for Spina Bifida

24 locations incl. Birmingham

Sponsor: David Chu

Sex: All·Age: 5+

Code: NCT07390318·Recruiting

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Impact of Patient Choice for Epidural Potency on Maternal Satisfaction

for Epidural Analgesia, Obstetric

1 location in Palo Alto

Sponsor: Stanford University

Sex: Female·Age: 18 - 50

Code: NCT07414407·Not Yet Recruiting

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndrome

18 locations incl. Orange

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07422480·Phase 3·Recruiting

Apply to this trial