Clinical Trials at Tufts Medical Center

As of June 2026, 123 paid clinical trials are recruiting at Tufts Medical Center, located at 800 WASHINGTON ST, BOX 790, BOSTON, MA 02111-1552, phone (617) 479-8053 in Boston, Massachusetts. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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123 clinical trials at Tufts Medical Center

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A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for Cancer Harboring BRAF Alterations

30 locations incl. Beverly Hills

Sponsor: Fore Biotherapeutics

Sex: All·Age: 10+

Code: NCT05503797·Phase 2·Recruiting

Apply to this trial

A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information

for Adult Growth Hormone Deficiency

29 locations incl. Phoenix

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT05718570·Enrolling By Invitation

Impella ECP Study (ECP Study) and Impella ECP Continued Access Protocol

for High-Risk Percutaneous Coronary Intervention

32 locations incl. Phoenix

Sponsor: Abiomed Inc.

Sex: All·Age: 18 - 90

Code: NCT05334784·Enrolling By Invitation

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for Clinical Stage III Cutaneous Melanoma AJCC v8

Drug: Cabozantinib

222 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05136196·Phase 2·Recruiting

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Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

for Atherosclerotic Cardiovascular Disease in Patients With ESKD

Drug: Clazakizumab

164 locations incl. Decatur

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT05485961·Phase 2, Phase 3·Recruiting

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Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

20 locations incl. Birmingham

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting

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A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

for Subacute Cutaneous Lupus Erythematosus

61 locations incl. Anniston

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT05531565·Phase 2, Phase 3·Recruiting

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

42 locations incl. Phoenix

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting

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Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

for Idiopathic Pulmonary Fibrosis

86 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 40+

Code: NCT04905693·Phase 3·Enrolling By Invitation

Pulmonary Artery Catheter in Cardiogenic Shock Trial

for Cardiogenic Shock

1 location in Boston

Sponsor: Tufts Medical Center

Sex: All·Age: 18 - 90

Code: NCT05485376·Recruiting

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Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF

for Idiopathic Pulmonary Fibrosis

20 locations incl. Mesa

Sponsor: Daewoong Pharmaceutical Co. LTD.

Sex: All·Age: 40+

Code: NCT05389215·Phase 2·Recruiting

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

1021 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

19 locations incl. Phoenix

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting

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Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease

for Proteinuric Kidney Disease

227 locations incl. Alabaster

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 10 - 65

Code: NCT05312879·Phase 2, Phase 3·Recruiting

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Allogenic Hepatocyte Transplantation Into Periduodenal Lymph Nodes

for End Stage Liver Disease

2 locations incl. Boston

Sponsor: LyGenesis, Inc.

Sex: All·Age: 18 - 70

Code: NCT04496479·Phase 2·Recruiting

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myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

for COPD

25 locations incl. Birmingham

Sponsor: Temple University

Sex: All·Age: 30+

Code: NCT05204888·Recruiting

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Aspiration in Acute Respiratory Failure Survivors 2

for Dysphagia

5 locations incl. Stanford

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT05108896·Recruiting

Apply to this trial

HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

for Hip Fractures

19 locations incl. Chandler

Sponsor: Population Health Research Institute

Sex: All·Age: 45+

Code: NCT04743765·Recruiting

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Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

for Breast Cancer, NOS

347 locations incl. Fairbanks

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 18 - 39

Code: NCT05108298·Recruiting

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JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

29 locations incl. Huntsville

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting

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Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for Recurrent Head and Neck Squamous Cell Carcinoma

178 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 79

Code: NCT04671667·Phase 2·Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

621 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

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Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

for Plasma Cell Myeloma

642 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT04566328·Phase 3·Recruiting

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A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

for Unresectable Head and Neck Squamous Cell Carcinoma

19 locations incl. Los Angeles

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT04534205·Phase 2, Phase 3·Recruiting

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NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

for Aortic Dissection

31 locations incl. Birmingham

Sponsor: Endospan Ltd.

Sex: All·Age: 18+

Code: NCT04471909·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

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A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

for PAH

Drug: Ralinepag

48 locations incl. Phoenix

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT03683186·Phase 3·Enrolling By Invitation

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

for Smoldering Plasma Cell Myeloma

Drug: Daratumumab

741 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT03937635·Phase 3·Recruiting

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A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

for Bronchopulmonary Dysplasia

26 locations incl. Little Rock

Sponsor: OHB Neonatology Ltd.

Sex: All·Age: 0 Hours - 24 Hours

Code: NCT03253263·Phase 2·Recruiting

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Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

for Non-Hodgkin Lymphoma

18 locations incl. Gilbert

Sponsor: Imugene Limited

Sex: All·Age: 18+

Code: NCT03666000·Phase 1·Recruiting

Apply to this trial

Cardiac Sarcoidosis Randomized Trial

for Cardiac Sarcoidosis

9 locations incl. New Haven

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18+

Code: NCT03593759·Phase 3·Recruiting

Apply to this trial

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

73 locations incl. Tucson

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting

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Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

Apply to this trial

Cardiogenic Shock Working Group Registry

for Cardiogenic Shock

16 locations incl. Weston

Sponsor: Tufts Medical Center

Sex: All·Age: 18+

Code: NCT04682483·Recruiting

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Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

for Grade 2 Meningioma

197 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT03180268·Phase 3·Recruiting

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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for Childhood Extracranial Germ Cell Tumor

566 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT03067181·Phase 3·Recruiting

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Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for Head and Neck Squamous Cell Carcinoma

676 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT02734537·Phase 2·Recruiting

Apply to this trial

Neuroblastoma Maintenance Therapy Trial

for Neuroblastoma

42 locations incl. Birmingham

Sponsor: Giselle Sholler

Sex: All·Age: 1 - 30

Code: NCT02679144·Phase 2·Recruiting

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Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

for Intracranial Meningioma

780 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT02523014·Phase 2·Recruiting

Apply to this trial

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

75 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting

Apply to this trial