Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF

Part of paid clinical trials in Mesa, Arizona.

Sponsor
Daewoong Pharmaceutical Co. LTD.
Study ID
NCT05389215
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

  • Idiopathic Pulmonary Fibrosis

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • DWN12088 — DRUG
    DWN12088 Xmg Tablet (BID)
  • Placebo — DRUG
    Placebo 0mg Tablet (BID)

Study Details

This is a randomized, double-blinded, placebo-controlled multicenter study to evaluate the safety and efficacy of DWN12088 in patients with Idiopathic Pulmonary Fibrosis.

Key Dates

Start date
Jul 29, 2022
Status verified
Jul 2025
Primary completion
Oct 13, 2026
Completion
Jan 30, 2027

Study Design

Enrollment
102 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: DWN12088 Xmg Tablet (BID)
    PRS inhibitor
  • Placebo Comparator: Placebo 0mg Tablet (BID)
    Placebo

Primary Outcome Measure

Rate of decline of FVC [ Time Frame: From Day 1 through Week 24 ]

Central Contacts

Locations (20)

FacilityCityStateZIPSite coordinators
Pulmonary Associates, PAMesaArizona85206-1346
Daewoong Pharmaceutical, Co.,Ltd
Dignity Health Norton Thoracic InstitutePhoenixArizona85013
Daewoong Pharmaceutical, Co.,Ltd
The University of California San FranciscoSan FranciscoCalifornia94143
Daewoong Pharmaceutical, Co.,Ltd
Loyola University Medical Center (LUMC)MaywoodIllinois60153
Daewoong Pharmaceutical, Co.,Ltd
University of Kansas Medical Center Research Institute, IncKansas CityKansas66160
Daewoong Pharmaceutical, Co.,Ltd
Beth Israel Deaconess Medical CenterBostonMassachusetts02215
Daewoong Pharmaceutical, Co.,Ltd
Tufts Medical CenterBostonMassachusetts02111
Daewoong Pharmaceutical, Co.,Ltd
University of Michigan Health SystemMichigan CenterMichigan48109
Daewoong Pharmaceutical, Co.,Ltd
The Lung Research Center, LLCChesterfieldMissouri63017
Daewoong Pharmaceutical, Co.,Ltd
Duke University Medical CenterDurhamNorth Carolina27705
Daewoong Pharmaceutical, Co.,Ltd
Pulmonix Research, LLCGreensboroNorth Carolina27403
Daewoong Pharmaceutical, Co.,Ltd
Legacy Research InstitutePortlandOregon97232
Daewoong Pharmaceutical, Co.,Ltd
Penn State Milton S. Hershey Medical CenterHersheyPennsylvania17033
Daewoong Pharmaceutical, Co.,Ltd
University of Pittsburgh Medical CenterPittsburghPennsylvania15213
Daewoong Pharmaceutical, Co.,Ltd
Lowcountry Lung and Critical CareCharlestonSouth Carolina29406
Daewoong Pharmaceutical, Co.,Ltd
The U.S. Department of Veterans AffairsCharlestonSouth Carolina29401
Daewoong Pharmaceutical, Co.,Ltd
Baylor Scott & White Research InstituteDallasTexas75204
Daewoong Pharmaceutical, Co.,Ltd
The University of Texas Southwestern Medical CenterDallasTexas75390-9020
Daewoong Pharmaceutical, Co.,Ltd
Baylor College of MedicineHoustonTexas77030
Daewoong Pharmaceutical, Co.,Ltd
The University of Texas Health San Antonio Medical Arts & Research CenterSan AntonioTexas78229-3901
Daewoong Pharmaceutical, Co.,Ltd

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By research site
Pulmonary Associates, PA· Mesa, AZDignity Health Norton Thoracic Institute· Phoenix, AZThe University of California San Francisco· San Francisco, CALoyola University Medical Center (LUMC)· Maywood, ILUniversity of Kansas Medical Center Research Institute, Inc· Kansas City, KSBeth Israel Deaconess Medical Center· Boston, MA

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