Solid tumor Clinical Trials in Boston, MA

As of June 2026, 120 paid clinical trials are recruiting for Solid tumor in Boston, Massachusetts. Recruiting Solid tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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120 clinical trials for Solid tumor

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A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

for Solid Tumor

12 locations incl. La Jolla

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06619587·Phase 1·Recruiting

Apply to this trial

First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

for Solid Tumors

3 locations incl. Boston

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06644755·Phase 1·Recruiting

Apply to this trial

Anti-GD2 ADC M3554 in Advanced Solid Tumors

for Advanced Solid Tumor

3 locations incl. Boston

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: 18+

Code: NCT06641908·Phase 1·Recruiting

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Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for Solid Tumor, Adult

19 locations incl. Duarte

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06625775·Phase 1·Recruiting

Apply to this trial

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

for Metastatic Solid Tumor

17 locations incl. Santa Monica

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06561685·Phase 1·Recruiting

Apply to this trial

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

for Solid Tumor

19 locations incl. Little Rock

Sponsor: NiKang Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06586957·Phase 1·Recruiting

Apply to this trial

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

for Advanced Solid Tumor

10 locations incl. Sarasota

Sponsor: Circle Pharma

Sex: All·Age: 12+

Code: NCT06577987·Phase 1·Recruiting

Apply to this trial

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

for Advanced Solid Tumor

11 locations incl. Irvine

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06147037·Phase 1·Recruiting

Apply to this trial

Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors

for Advanced Solid Tumors

4 locations incl. Palo Alto

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06532565·Phase 1·Recruiting

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A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

for Locally Advanced Solid Tumor

17 locations incl. Irvine

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06521554·Phase 1·Recruiting

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

for Solid Tumors

18 locations incl. Birmingham

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06431594·Phase 1·Recruiting

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for Metastatic Solid Tumor

Drug: LY4052031

17 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06465069·Phase 1·Recruiting

Apply to this trial

Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and Tuvusertib (M1774) for Advanced Solid Tumors

for Advanced Malignant Solid Neoplasm

Drug: Peposertib

6 locations incl. Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687136·Phase 1·Recruiting

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Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

for Melanoma Stage IV

11 locations incl. Scottsdale

Sponsor: Georgiamune Inc

Sex: All·Age: 18+

Code: NCT06425926·Phase 1, Phase 2·Recruiting

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Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

for Advanced Solid Tumor

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06302621·Phase 1·Recruiting

Apply to this trial

First In Human Study of CX-2051 in Advanced Solid Tumors

for Solid Tumor, Adult

7 locations incl. Denver

Sponsor: CytomX Therapeutics

Sex: All·Age: 18+

Code: NCT06265688·Phase 1·Recruiting

Apply to this trial

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

for Solid Tumor, Adult

15 locations incl. Birmingham

Sponsor: Corbus Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06265727·Phase 1, Phase 2·Recruiting

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Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for Non-small Cell Lung Cancer

18 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06218914·Phase 1·Recruiting

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First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer

for Advanced Cancer

13 locations incl. Encinitas

Sponsor: OnKure, Inc.

Sex: All·Age: 18+

Code: NCT06239467·Phase 1·Recruiting

Apply to this trial

A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors

for Advanced Solid Tumor

20 locations incl. Irvine

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06244485·Phase 1·Recruiting

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A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for Advanced Solid Tumors With KRAS G12C Mutations

15 locations incl. La Jolla

Sponsor: Frontier Medicines Corporation

Sex: All·Age: 18+

Code: NCT06244771·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

for Ovarian Cancer

14 locations incl. Denver

Sponsor: OnCusp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06234423·Phase 1·Recruiting

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Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

for Advanced Solid Tumor

4 locations incl. Bethesda

Sponsor: Ankyra Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06171750·Phase 1·Recruiting

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Study of GS-0201 Alone and in Combination in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

4 locations incl. Boston

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06167317·Phase 1·Recruiting

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A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

for Solid Tumors

Drug: INCB161734

16 locations incl. Phoenix

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06179160·Phase 1·Recruiting

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Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations

for Locally Advanced Cholangiocarcinoma

4 locations incl. San Francisco

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06160752·Phase 1·Recruiting

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Phase 1 Study of Intratumoral Administration of VAX014 With Expansion in Combination With a Checkpoint Inhibitor in Subjects With Advanced Solid Tumors

for Advanced Solid Tumor

7 locations incl. Tucson

Sponsor: Vaxiion Therapeutics

Sex: All·Age: 18+

Code: NCT05901285·Phase 1·Recruiting

Apply to this trial

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

for Advanced Solid Tumors

7 locations incl. Los Angeles

Sponsor: LigaChem Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05941507·Phase 1, Phase 2·Recruiting

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Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

for Non-small Cell Lung Cancer (NSCLC)

17 locations incl. Sacramento

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06040541·Phase 1·Recruiting

Apply to this trial

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

for Advanced Solid Tumor

15 locations incl. Sacramento

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05785741·Phase 1, Phase 2·Recruiting

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Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

for Anatomic Stage III Breast Cancer AJCC v8

7 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT05372640·Phase 1·Recruiting

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A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

for Wilms Tumor

Drug: Selinexor

16 locations incl. Los Angeles

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 12 Months+

Code: NCT05985161·Phase 2·Recruiting

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A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

for Solid Tumors

11 locations incl. Los Angeles

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05836324·Phase 1·Recruiting

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Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

for Metastatic Malignant Solid Neoplasm

22 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687110·Phase 1·Recruiting

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FOG-001 in Locally Advanced or Metastatic Solid Tumors

for Cancer

31 locations incl. Phoenix

Sponsor: Parabilis Medicines, Inc.

Sex: All·Age: 18+

Code: NCT05919264·Phase 1, Phase 2·Recruiting

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VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

for Solid Tumor

Drug: Atezolizumab

7 locations incl. Chicago

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 6 Months - 30

Code: NCT04796012·Phase 1, Phase 2·Recruiting

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Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for Non-small Cell Lung Cancer

10 locations incl. Gilbert

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT05786924·Phase 1, Phase 2·Recruiting

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

475 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting

Apply to this trial

Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer

for Breast Cancer

15 locations incl. Orlando

Sponsor: Incyclix Bio

Sex: All·Age: 18+

Code: NCT05735080·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

for Solid Tumor, Adult

13 locations incl. Los Angeles

Sponsor: GV20 Therapeutics

Sex: All·Age: 18+

Code: NCT05669430·Phase 1, Phase 2·Recruiting

Apply to this trial