Neurology Clinical Trials in Boston, MA

As of June 2026, 160 paid clinical trials are recruiting for Neurology in Boston, Massachusetts. Neurology trials investigate disease-modifying therapies for Alzheimer's, Parkinson's, multiple sclerosis, ALS, and stroke recovery alongside symptomatic treatments for epilepsy, migraine, and cognitive decline. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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160 clinical trials for Neurology

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Dance and Energy Expenditure Among Adults With Parkinson's

for Parkinson Disease

1 location in Boston

Sponsor: Northeastern University

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06425731·Recruiting

Apply to this trial

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

for Epilepsy in Children

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 18

Code: NCT06585605·Recruiting

Apply to this trial

Dalfampridine Combined With Physical Therapy for Mobility Impairment in Multiple Sclerosis

for Multiple Sclerosis

1 location in Boston

Sponsor: MGH Institute of Health Professions

Sex: All·Age: 25 - 75

Code: NCT06136728·Phase 4·Recruiting

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A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

for Parkinson Disease

27 locations incl. Irvine

Sponsor: AskBio Inc

Sex: All·Age: 45 - 75

Code: NCT06285643·Phase 2·Recruiting

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A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

for Multiple Sclerosis

17 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18 - 60

Code: NCT06220201·Phase 1·Recruiting

Apply to this trial

Strategy for Improving Stroke Treatment Response

for Ischemic Stroke

52 locations incl. Birmingham

Sponsor: Translational Sciences, Inc.

Sex: All·Age: 18+

Code: NCT05948566·Phase 2·Recruiting

Apply to this trial

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People At Risk for Alzheimer's Disease

for Alzheimer Disease

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05776641·Recruiting

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Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

for Mild Traumatic Brain Injury

1 location in Boston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 65

Code: NCT06109909·Recruiting

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Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

for Alzheimer Disease

1 location in Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT06094192·Recruiting

Apply to this trial

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

25 locations incl. Phoenix

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting

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Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

for Dementia

1 location in Boston

Sponsor: Hebrew SeniorLife

Sex: All·Age: 60 - 106

Code: NCT05950607·Recruiting

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Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

for Anarthria

2 locations incl. Stanford

Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All·Age: 18 - 80

Code: NCT05724173·Recruiting

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Impact of Intensive Computerized Cognitive Training

for Acquired Brain Injury

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 25 - 65

Code: NCT06130735·Recruiting

Apply to this trial

CTSN Embolic Protection Trial

for Delirium

24 locations incl. North Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting

Apply to this trial

Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium

for Delirium, Postoperative

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 70+

Code: NCT06052397·Recruiting

Apply to this trial

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

for Epilepsy

4 locations incl. Miami

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04419272·Phase 4·Recruiting

Apply to this trial

Cognitive Neurology Unit Clinical Registry

for Alzheimer Disease

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 50 - 95

Code: NCT05925621·Recruiting

Apply to this trial

Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

Effects of Antiviral Therapies on Epstein-Barr Virus Replication

for Multiple Sclerosis

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05957913·Phase 2·Enrolling By Invitation

Triage Survey for Neurology Research Eligibility

for Alzheimer Disease

3 locations incl. Boston

Sponsor: Adams Clinical

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06104852·Recruiting

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An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation

for Stroke

2 locations incl. Boston

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04187131·Recruiting

Apply to this trial

Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

for Subjective Cognitive Concerns

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT05881239·Recruiting

Apply to this trial

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

for Alzheimer Disease

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 40 - 99·Accepts healthy volunteers

Code: NCT06538311·EARLY_Phase 1·Recruiting

Apply to this trial

Moderators and Mediators of Perceptual Learning

for Cognitive Change

3 locations incl. Riverside

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT05894967·Recruiting

Apply to this trial

Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)

for Alzheimer's Disease

2 locations incl. Boston

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 120

Code: NCT05658913·Recruiting

Apply to this trial

Pilot/Pivotal Study of DBS+Rehab After Stroke

for Stroke

10 locations incl. Phoenix

Sponsor: Enspire DBS Therapy, Inc.

Sex: All·Age: 21+

Code: NCT05701280·Recruiting

Apply to this trial

Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

for Dementia

1 location in Boston

Sponsor: Hebrew SeniorLife

Sex: All·Age: 55+

Code: NCT05661084·Recruiting

Apply to this trial

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

for Multiple Sclerosis

12 locations incl. New Haven

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55

Code: NCT05285891·Phase 4·Recruiting

Apply to this trial

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

for Diabetes

27 locations incl. Phoenix

Sponsor: Marinella Temprosa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05704309·Enrolling By Invitation

North American Prodromal Synucleinopathy Consortium Stage 2

for REM Sleep Behavior Disorder

8 locations incl. Los Angeles

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05826457·Enrolling By Invitation

Gamma-Music Based Intervention for Mild Alzheimer's Disease

for Alzheimer Disease

1 location in Boston

Sponsor: Northeastern University

Sex: All·Age: 50 - 95·Accepts healthy volunteers

Code: NCT05984524·Recruiting

Apply to this trial

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

for Amyloid Plaque

13 locations incl. Phoenix

Sponsor: AC Immune SA

Sex: All·Age: 35 - 85

Code: NCT05462106·Phase 1, Phase 2·Recruiting

Apply to this trial

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for Stroke

45 locations incl. Birmingham

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05338697·Recruiting

Apply to this trial

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

for Dystonia

1 location in Boston

Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05317390·Recruiting

Apply to this trial

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

for Hereditary Spastic Paraplegia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1 Month - 30

Code: NCT05354622·Recruiting

Apply to this trial

Assess Fibrin in Brains With AD/ADRD

for Alzheimer Disease

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05336695·Phase 1, Phase 2·Recruiting

Apply to this trial

Improving Visual Field Deficits With Noninvasive Brain Stimulation

for Visual Field Defect, Peripheral

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18 - 80

Code: NCT05085210·Recruiting

Apply to this trial

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

for Tuberous Sclerosis Complex

11 locations incl. Birmingham

Sponsor: Darcy Krueger

Sex: All·Age: 1 Day - 6 Months

Code: NCT05104983·Phase 2·Recruiting

Apply to this trial

Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

Apply to this trial

A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

24 locations incl. Paradise Valley

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04951622·Phase 3·Recruiting

Apply to this trial

Conditions in Neurology (Boston, MA)

Stroke· 29 Alzheimer's disease· 22 Parkinson's disease· 22 Epilepsy· 17 Multiple sclerosis· 16 ALS (amyotrophic lateral sclerosis)· 15 Mild cognitive impairment (MCI)· 12 Dementia· 10 Cognitive impairment / decline· 9 Multiple system atrophy· 8 Movement disorders· 8 Myasthenia gravis· 7 Traumatic brain injury (TBI)· 5 Essential tremor· 4 Huntington disease· 3 Spinal cord injury· 3 Migraine· 2