Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Boston University Charles River Campus
Study ID
NCT06094192
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - 100 Years
Healthy Volunteers
Accepted

Interventions

  • High definition transcranial electrical current stimulation — DEVICE
    Low-intensity and safe, noninvasive application of electrical current to the human scalp with the goal of gradually modulating levels of neuronal excitability.

Study Details

The investigators will evaluate the theory that Alzheimer's disease-related memory impairment derives from the inefficient orchestration of rhythmic activity at the level of large-scale cortical networks. The results as expected to elucidate AD-related pathophysiology and set groundwork for the development of drug-free interventions for improving memory in AD and related dementias.

Key Dates

Start date
Dec 20, 2023
Status verified
Sep 2025
Primary completion
May 31, 2028
Completion
May 31, 2028

Study Design

Enrollment
204 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: active stimulation
    Memory performance data is collected during active brain stimulation and reported 1 year later
  • Sham Comparator: sham stimulation
    Memory performance data is collected during sham brain stimulation and reported 1 year later

Primary Outcome Measure

Memory performance (active stimulation condition) [ Time Frame: Time Frame: Memory performance data is collected during active brain stimulation and reported 1 year later ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
677 Beacon St. Room 308BostonMassachusetts02215
Robert Reinhart, PhD
[email protected]
617-353-9481

Find similar trials in Boston, MA

By condition
Alzheimer's disease
By specialty
NeurologyDementia careBrain disordersGeriatrics
By research site
677 Beacon St. Room 308· Boston, MA

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