Endocrinology Clinical Trials in Boston, MA

As of June 2026, 80 paid clinical trials are recruiting for Endocrinology in Boston, Massachusetts. Endocrinology trials investigate next-generation GLP-1 and GIP agonists, novel insulin formulations, beta-cell replacement therapies, and metabolic interventions across diabetes, obesity, and thyroid disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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80 clinical trials for Endocrinology

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Best Practice Advisories to Reduce Inequities in Technology Use for People With Type 1 Diabetes

for Diabetes Mellitus, Type 1

2 locations incl. Boston

Sponsor: T1D Exchange, United States

Sex: All·Age: 2 - 95·Accepts healthy volunteers

Code: NCT06931275·Recruiting

Apply to this trial

Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline

for Overweight, Childhood

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 4 - 17

Code: NCT06432790·Recruiting

Apply to this trial

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

for Diabetes Mellitus, Type 1

60 locations incl. Scottsdale

Sponsor: vTv Therapeutics

Sex: All·Age: 18+

Code: NCT06334133·Phase 3·Recruiting

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Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

for Biliary Tract Cancer

6 locations incl. Denver

Sponsor: ModeX Therapeutics, An OPKO Health Company

Sex: All·Age: 18+

Code: NCT06239194·Phase 1, Phase 2·Recruiting

Apply to this trial

Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes

for Diabetes Mellitus, Type 1

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 5 - 12

Code: NCT05899166·Recruiting

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Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease

for Type 2 Diabetes

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 80

Code: NCT06190158·EARLY_Phase 1·Recruiting

Apply to this trial

Digital Health Navigation for Latino Patients With Type II Diabetes

for Type 2 Diabetes

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06283992·Recruiting

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GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

for Genetic Predisposition

Drug: Semaglutide

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06003153·Phase 4·Recruiting

Apply to this trial

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for Diabetes Mellitus, Type 2

124 locations incl. Chandler

Sponsor: Cleerly, Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06112418·Recruiting

Apply to this trial

Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

for Diabetes

21 locations incl. Dothan

Sponsor: Sonavex, Inc.

Sex: All·Age: 18 - 84

Code: NCT06190717·Recruiting

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FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS)

for Type 1 Diabetes Mellitus

Drug: Frexalimab

14 locations incl. San Francisco

Sponsor: Sanofi

Sex: All·Age: 12 - 35

Code: NCT06111586·Phase 2·Recruiting

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Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment

for Overweight and Obesity

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06069622·Recruiting

Apply to this trial

Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure

for Obesity

1 location in Boston

Sponsor: Christopher C. Thompson, MD, MSc

Sex: All·Age: 18 - 70

Code: NCT05711758·Recruiting

Apply to this trial

DFC 004 Biomarkers for Active Diabetic Foot Ulcers

for Diabetic Foot Ulcer

8 locations incl. Tucson

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06104969·Recruiting

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Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

for Non-small Cell Lung Cancer

10 locations incl. Gilbert

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT05786924·Phase 1, Phase 2·Recruiting

Apply to this trial

Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression

for Diabetes

2 locations incl. Boston

Sponsor: Albert Einstein College of Medicine

Sex: All·Age: 18 - 64

Code: NCT05734313·Recruiting

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Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

for Overweight

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65

Code: NCT05799222·Recruiting

Apply to this trial

Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

for Thyroid Cancer

6 locations incl. Washington D.C.

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12+

Code: NCT05668962·Phase 2·Recruiting

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Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children

for Obesity

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 9 - 12·Accepts healthy volunteers

Code: NCT05464186·Recruiting

Apply to this trial

PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life

for Type 1 Diabetes

4 locations incl. Aurora

Sponsor: University of Colorado, Denver

Sex: All·Age: 0 Days - 99·Accepts healthy volunteers

Code: NCT06141434·Recruiting

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A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

for Melanoma

58 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 16+

Code: NCT05538130·Phase 1·Recruiting

Apply to this trial

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

for Diabetes

27 locations incl. Phoenix

Sponsor: Marinella Temprosa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05704309·Enrolling By Invitation

Boosting Emotional Well-being and Happiness in Outpatients Living With Diabetes

for Diabetes Mellitus, Type 2

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05420051·Recruiting

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Endoscopic Metabolic and Bariatric Therapies

for Obesity

1 location in Boston

Sponsor: Christopher C. Thompson, MD, MSc

Sex: All·Age: 18 - 80

Code: NCT05725967·Enrolling By Invitation

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

for Melanoma

31 locations incl. Fayetteville

Sponsor: Pfizer

Sex: All·Age: 16+

Code: NCT05355701·Phase 1·Recruiting

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Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

for Endometrial Carcinoma

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+

Code: NCT04839614·Recruiting

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Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease

for Non-Alcoholic Fatty Liver Disease

2 locations incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT05728697·Recruiting

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A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

for Diabetes Mellitus, Type 1

12 locations incl. Duarte

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT04786262·Phase 3·Recruiting

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International Weight Control Registry

for Weight Loss

7 locations incl. Birmingham

Sponsor: Tufts University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04907396·Recruiting

Apply to this trial

Rare and Atypical Diabetes Network

for Diabetes Mellitus

13 locations incl. Aurora

Sponsor: University of South Florida

Sex: All·Age: All ages

Code: NCT05544266·Recruiting

Apply to this trial

The Physiology of Human Brown Adipose Tissue

for Adipose Tissue, Brown

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT04352244·Recruiting

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RESET System Pivotal Trial (Rev F)

for Diabetes type2

7 locations incl. Washington D.C.

Sponsor: Morphic Medical Inc.

Sex: All·Age: 22 - 65

Code: NCT04101669·Recruiting

Apply to this trial

Kidney Precision Medicine Project

for Acute Kidney Failure

13 locations incl. Tucson

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04334707·Recruiting

Apply to this trial

The T1D Exchange Registry

for Diabetes Mellitus, Type 1

1 location in Boston

Sponsor: T1D Exchange, United States

Sex: All·Age: All ages

Code: NCT04629586·Recruiting

Apply to this trial

Imaging Histone Deacetylase in the Heart

for Heart Failure With Normal Ejection Fraction

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT03549559·Recruiting

Apply to this trial

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for Solid Tumors

6 locations incl. Los Angeles

Sponsor: Apollomics Inc.

Sex: All·Age: 18+

Code: NCT03175224·Phase 2·Recruiting

Apply to this trial

Type 1 Diabetes Extension Study

for Type 1 Diabetes Mellitus

12 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 8 - 35

Code: NCT02734277·Recruiting

Apply to this trial

Hereditary Risk Factors for Thyroid Cancer

for Thyroid Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT02747888·Recruiting

Apply to this trial

Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.

for Obesity

2 locations incl. Boston

Sponsor: Columbia University

Sex: All·Age: Up to 80

Code: NCT01998750·Recruiting

Apply to this trial

TrialNet Pathway to Prevention of T1D

for Diabetes Mellitus, Type 1

17 locations incl. Orange

Sponsor: University of South Florida

Sex: All·Age: 2 - 45·Accepts healthy volunteers

Code: NCT00097292·Recruiting

Apply to this trial

Conditions in Endocrinology (Boston, MA)

Obesity / overweight· 27 Type 1 diabetes· 21 Diabetes (general / unspecified)· 16 Type 2 diabetes· 13 Thyroid cancer· 8 Metabolic syndrome· 6 Prediabetes· 4 Gestational diabetes· 1 Insulin resistance· 1