Clinical Trials at University of Alabama at Birmingham

As of June 2026, 349 paid clinical trials are recruiting at University of Alabama at Birmingham, located at 619 19TH ST S, BIRMINGHAM, AL 35249-0001, phone (205) 934-6249 in Birmingham, Alabama. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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349 clinical trials at University of Alabama at Birmingham

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The Impact of Expressive Emotional Writing on Facilitating Grief Resolution in Adults With Spinal Cord Injury

for Spinal Cord Injuries

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06147258·Recruiting

Apply to this trial

A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

33 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 12+

Code: NCT06338995·Phase 3·Recruiting

Apply to this trial

Long COVID Brain Fog: Cognitive Rehabilitation Trial

for Long COVID

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT06095297·Recruiting

Apply to this trial

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

for Kidney Stone

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 70

Code: NCT06330246·Recruiting

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Gut Oxalate Absorption in Calcium Oxalate Stone Disease

for Kidney Stone

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06331546·Recruiting

Apply to this trial

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

61 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting

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A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

for Pulmonary Fibrosis

59 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06329401·Phase 2·Recruiting

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A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

for Multiple Sclerosis

17 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18 - 60

Code: NCT06220201·Phase 1·Recruiting

Apply to this trial

Implementation Trial to Evaluate a Population Health Combination Intervention to Meet HIV Testing, Linkage, and Viral Suppression Goals in Alabama

for HIV

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT05384145·Recruiting

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The Patient and Family Centered I-PASS LISTEN Study: Language, Inclusion, Safety, and Teamwork for Equity Now

for Communication

8 locations incl. Birmingham

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT05591066·Recruiting

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Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

for Polycythemia Vera

Drug: Givinostat

14 locations incl. Birmingham

Sponsor: Italfarmaco

Sex: All·Age: 18+

Code: NCT06093672·Phase 3·Recruiting

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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

41 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting

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A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures

for Functional Seizures

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 11 - 18

Code: NCT05819268·Recruiting

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Retraining and Control Therapy (ReACT) R33 Phase

for Convulsion, Non-Epileptic

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 11 - 18·Accepts healthy volunteers

Code: NCT06007053·Recruiting

Apply to this trial

Pulsed Lavage in Implant-Based Breast Reconstruction

for Breast Reconstruction

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18 - 75

Code: NCT05585710·Recruiting

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A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

for Multiple Myeloma

17 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06121843·Phase 1·Recruiting

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Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

12 locations incl. Birmingham

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 40+

Code: NCT05975983·Phase 2·Recruiting

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High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV

for HIV

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT05965518·Recruiting

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Safety and Efficacy of Carbon Dioxide Gas for Endoscopy

for Abdominal Pain

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 6 Months - 18

Code: NCT06134154·Recruiting

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A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma

for Relapsed and/or Refractory Multiple Myeloma

13 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06153251·Phase 1·Recruiting

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Stimulus-Evoked Directional Field Potentials to Guide Subthalamic and Pallidal DBS for PD

for Parkinson Disease

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 89

Code: NCT06169852·Recruiting

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Molecular Residual Disease (MRD) Guided Adjuvant ThErapy in Renal Cell Carcinoma (RCC)

for Renal Cell Carcinoma

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT06005818·Phase 2·Recruiting

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Sequential Therapy in Multiple Myeloma Guided by MRD Assessments

for Multiple Myeloma

10 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT05231629·Phase 2·Recruiting

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CAMELLIA Cohort: A Longitudinal Study to Understand Sexual Health and Prevention Among Women in Alabama

for Hiv

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 89

Code: NCT05463692·Enrolling By Invitation

Evaluation of the GORE® Ascending Stent Graft

for Aortic Aneurysm, Thoracic

41 locations incl. Birmingham

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05800743·Enrolling By Invitation

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for Hereditary Hemorrhagic Telangiectasia

16 locations incl. Birmingham

Sponsor: Cure HHT

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06259292·Recruiting

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Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for Heart Failure

31 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40 - 85

Code: NCT06122779·Phase 2·Recruiting

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Community Health Worker Based Intervention to Improve Palliative Care

for Cancer

4 locations incl. Birmingham

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05407844·Enrolling By Invitation

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

for Tobacco Use Disorder

3 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT05452772·Phase 2·Recruiting

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A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer

for Metastatic Breast Cancer

12 locations incl. Birmingham

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06099769·Phase 2·Recruiting

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Making Intergenerational Connections Through Arts

for Older Adults

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT05986149·Recruiting

Apply to this trial

Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies

for Acute Myeloid Leukemia

5 locations incl. Birmingham

Sponsor: Vincerx Pharma, Inc.

Sex: All·Age: 18+

Code: NCT06034275·Phase 1·Recruiting

Apply to this trial

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for Primary Biliary Cholangitis

49 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06051617·Phase 3·Recruiting

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A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial

for Acute Kidney Injury

9 locations incl. Birmingham

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05805709·Recruiting

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Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV

for HIV Infections

3 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT06013579·Recruiting

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A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

for Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations

18 locations incl. Birmingham

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05967689·Phase 2·Recruiting

Apply to this trial

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

for Glioblastoma, IDH-wildtype

8 locations incl. Birmingham

Sponsor: Orbus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05879367·Phase 1·Recruiting

Apply to this trial

Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

19 locations incl. Birmingham

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting

Apply to this trial

Determining the Role of Social Reward Learning in Social Anhedonia

for Psychosis

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 35

Code: NCT05617898·Recruiting

Apply to this trial

Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation