Clinical Trials at University of Michigan

As of June 2026, 435 paid clinical trials are recruiting at University of Michigan, located at 1500 E MEDICAL CENTER DR, ANN ARBOR, MI 48109-5000, phone (734) 615-9888 in Ann Arbor, Michigan. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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435 clinical trials at University of Michigan

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Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

for Cardiovascular Diseases

37 locations incl. Little Rock

Sponsor: BrioHealth Solutions, Inc.

Sex: All·Age: 18 - 100

Code: NCT06310031·Recruiting

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A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

for Primary Myelofibrosis

13 locations incl. Palo Alto

Sponsor: Ajax Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06343805·Phase 1·Recruiting

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Long-term Evaluation of Nasopharyngeal Airway in Hypotonia

for Hypotonia, Muscle

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 3 - 23

Code: NCT06614582·Enrolling By Invitation

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Drug: Vosoritide

35 locations incl. California City

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06382155·Phase 2·Recruiting

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Open-Label Extension Study of Setmelanotide

for Obesity Associated With Defects in Leptin-melanocortin Pathway

13 locations incl. Scottsdale

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 2+

Code: NCT06596135·Phase 3·Enrolling By Invitation

Community Based Treatment for (ComBaT) Glaucoma

for Glaucoma

2 locations incl. Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 40+

Code: NCT06124521·Recruiting

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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for Colorectal Neoplasms

Drug: Amivantamab

79 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06662786·Phase 3·Recruiting

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Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors

for Specific Advanced Solid Tumors

15 locations incl. Phoenix

Sponsor: Acrivon Therapeutics

Sex: All·Age: 18+

Code: NCT06667141·Phase 1·Recruiting

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Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils

for Otolaryngological Disease

2 locations incl. Ann Arbor

Sponsor: Oregon Health and Science University

Sex: All·Age: 2 - 17

Code: NCT06258837·Recruiting

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Empower@Home: Hybrid Effectiveness-Implementation Randomized Controlled Trial (RCT)

for Depression

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 50+

Code: NCT06584422·Recruiting

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TENS in Scleroderma

for Scleroderma

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06646913·Phase 1·Recruiting

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Fibromyalgia Sleep A to ZZZ Study

for Fibromyalgia

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06567886·Recruiting

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Efficacy-Implementation Study for PC CARES in Rural Alaska

for Suicide Prevention

2 locations incl. Fairbanks

Sponsor: University of Michigan

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT06658808·Recruiting

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A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B

for Hemophilia B

14 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 2+

Code: NCT06379789·Phase 1, Phase 2·Recruiting

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A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for Melanoma

104 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06246916·Phase 3·Recruiting

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Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

18 locations incl. Los Angeles

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting

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A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

for Multiple Myeloma

50 locations incl. Gilbert

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18+

Code: NCT06413498·Phase 3·Recruiting

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Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

for Adenoid Cystic Carcinoma

8 locations incl. Boston

Sponsor: Rgenta Therapeutics Inc

Sex: All·Age: 18+

Code: NCT06462183·Phase 1·Recruiting

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Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder

for Bipolar Disorder

1 location in Ann Arbor

Sponsor: Leslie Swanson

Sex: All·Age: 18 - 60

Code: NCT06226025·Phase 2·Recruiting

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Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

for Extensive-stage Small-cell Lung Cancer

Drug: Atezolizumab

3 locations incl. Los Angeles

Sponsor: Kamya Sankar

Sex: All·Age: All ages

Code: NCT05588388·Phase 2·Recruiting

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A Study to Assess Growth in Children With Idiopathic Short Stature

for Idiopathic Short Stature

40 locations incl. Phoenix

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 16

Code: NCT06309979·Recruiting

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A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

13 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06313593·Phase 1·Recruiting

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The APS Phenotyping Study

for ARDS

20 locations incl. Fresno

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06521502·Recruiting

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting

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PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting

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A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement

for Endogenous Cushing Syndrome

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 75

Code: NCT06430528·Recruiting

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Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)

for Essential Thrombocythemia

22 locations incl. Glendale

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06456346·Phase 3·Recruiting

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Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT

for Regional Citrate Anticoagulation (RCA)

14 locations incl. Birmingham

Sponsor: Vantive Health LLC

Sex: All·Age: 18+

Code: NCT05399537·Phase 3·Recruiting

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RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

for Systemic Sclerosis

10 locations incl. New Haven

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 75

Code: NCT06328777·Phase 1, Phase 2·Recruiting

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Dime La VerDAD: Verify, Debunk, and Disseminate

for Influenza

4 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT06417762·Recruiting

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

73 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting

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Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

for Acute Respiratory Distress Syndrome

33 locations incl. Tucson

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06066502·Phase 3·Recruiting

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Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

for Triple-Negative Breast Cancer

88 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06393374·Phase 3·Recruiting

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A Trial of Lu AG13909 in Adult Participants With Cushing's Disease

for Cushing's Disease

1 location in Ann Arbor

Sponsor: H. Lundbeck A/S

Sex: All·Age: 18 - 70

Code: NCT06471829·Phase 2·Recruiting

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A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

for Colorectal Cancer

9 locations incl. Duarte

Sponsor: Apollo Therapeutics Ltd

Sex: All·Age: 18+

Code: NCT06399757·Phase 1, Phase 2·Recruiting

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Study of SGR-3515 In Participants With Advanced Solid Tumors.

for Advanced Solid Tumor

13 locations incl. New Haven

Sponsor: Schrödinger, Inc.

Sex: All·Age: 18+

Code: NCT06463340·Phase 1·Recruiting

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

22 locations incl. Phoenix

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for Crohn's Disease

Drug: Tulisokibart

87 locations incl. Dothan

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 16 - 80

Code: NCT06430801·Phase 3·Recruiting

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Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

for Metastatic Breast Cancer

29 locations incl. Phoenix

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06324357·Phase 1, Phase 2·Recruiting

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Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy

for Pain, Postoperative

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06384664·Recruiting

Apply to this trial