Paid Clinical Trials in Alabama

Alabama has 1,359 paid clinical trials enrolling now across cities including Birmingham, Mobile and Huntsville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,359 clinical trials

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A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

for Chronic Obstructive Pulmonary Disease

Drug: Dupilumab

9 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 40 - 85

Code: NCT07053423·Phase 4·Recruiting

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Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

for Plaque Psoriasis

Drug: Deucravacitinib

122 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40+

Code: NCT07116967·Phase 3·Recruiting

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Digital Intervention for Physical Activity

for Depression - Major Depressive Disorder

1 location in Auburn

Sponsor: Auburn University

Sex: All·Age: 19 - 40

Code: NCT07130734·Recruiting

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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for High Risk Cardiovascular Disease

Drug: Zilebesiran

247 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07181109·Phase 3·Recruiting

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Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

for Cystic Fibrosis (CF)

18 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 12+

Code: NCT06837181·Recruiting

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DESTINY-PANTUMOUR04

for Adenocarcinoma (NOS)

17 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07124000·Recruiting

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A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for Alzheimers Disease

Drug: Trontinemab

35 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07169578·Phase 3·Recruiting

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Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

for Chronic Obstructive Pulmonary Disease

Drug: Lunsekimig

54 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 40 - 80

Code: NCT07190222·Phase 3·Recruiting

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Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial

for Prematurity

4 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 6 Hours - 4 Days

Code: NCT06420531·Recruiting

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Improving Needs Among Older Adults

for Critical Illness

4 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06588556·Recruiting

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Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome

for Cascade Testing

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07106359·Enrolling By Invitation

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

for PARKINSON DISEASE (Disorder)

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 80

Code: NCT07557706·Recruiting

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A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

for Interstitial Lung Diseases

Drug: Nerandomilast

33 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06806592·Phase 3·Recruiting

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Remote Oximeter Monitoring Post-discharge to Reduce Emergency Room Visits and Rehospitalization

for Emergencies

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 22 Weeks - 6 Months

Code: NCT06565390·Recruiting

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Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

for Atrial Fibrillation (AF)

18 locations incl. Birmingham

Sponsor: Arga Medtech SA

Sex: All·Age: 18 - 80

Code: NCT06784466·Recruiting

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The Effect of Light Intervention on Recovery in Individuals With Opioid Use Disorder (OUD)

for Opioid Use Disorder

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06832007·Recruiting

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Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

for Hepatocellular Carcinoma (HCC)

13 locations incl. Birmingham

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT06726161·Phase 1, Phase 2·Recruiting

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Genetic Variation in IgG in Alpha 1 Antitrypsin Deficiency

for Alpha 1-Antitrypsin

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 19+

Code: NCT07135427·Phase 4·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for Colorectal Cancer

22 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07023289·Phase 2·Recruiting

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Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

for Neurofibromatosis 1

Drug: Selumetinib

15 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 - 8

Code: NCT06188741·Phase 2·Recruiting

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A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

109 locations incl. Birmingham

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting

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A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

for Invasive Mold Infections

15 locations incl. Birmingham

Sponsor: Basilea Pharmaceutica

Sex: All·Age: 18+

Code: NCT06925321·Phase 3·Recruiting

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The ARISE Study - Use of Vertical Positioning

for Acute Respiratory Distress Syndrome

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 80

Code: NCT07025421·Recruiting

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BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

for Healthy

114 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 1 Day - 49·Accepts healthy volunteers

Code: NCT07160244·Phase 3·Recruiting

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OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

for Cardiovascular Disease

Drug: Olpasiran

204 locations incl. Alexander City

Sponsor: Amgen

Sex: All·Age: 50 - 105

Code: NCT07136012·Phase 3·Recruiting

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Activities to Change Your Mood: A Test of the Acceptability and Initial Efficacy in Clinical Samples and Healthy Controls

for Schizophrenia Disorders

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06911723·Recruiting

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Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS)

for Bronchiectasis Adult

3 locations incl. Birmingham

Sponsor: Synchrony-Medical, Ltd

Sex: All·Age: 21+

Code: NCT07135284·Recruiting

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Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)

for COPD Acute Exacerbation

22 locations incl. Birmingham

Sponsor: Connect Biopharm LLC

Sex: All·Age: 40 - 80

Code: NCT06940154·Phase 2·Recruiting

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The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

for Sickle Cell Disease

14 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 10 - 65

Code: NCT06975865·Phase 3·Recruiting

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A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

for Narcolepsy Type 1

Drug: ORX750

19 locations incl. Auburn

Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All·Age: 18 - 65

Code: NCT07096674·Phase 2·Recruiting

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Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults

for Prurigo Nodularis

Drug: Nemolizumab

39 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT06988618·Recruiting

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A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type 1

109 locations incl. Cullman

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07076199·Phase 3·Recruiting

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Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT

for Refractory Ventricular Tachycardia

5 locations incl. Birmingham

Sponsor: Thermedical, Inc.

Sex: All·Age: 18+

Code: NCT05337241·Recruiting

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Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

for Multiple Myeloma, Newly Diagnosed

11 locations incl. Birmingham

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 19+

Code: NCT06974786·Phase 2·Recruiting

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Safety and Efficacy of Boric Acid Inserts for Treatment of Vulvovaginal Candidiasis

for Vulvovaginal Candidiases

27 locations incl. Mobile

Sponsor: pH-D Feminine Health LLC

Sex: Female·Age: 12+

Code: NCT07109869·Phase 3·Recruiting

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REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam

for Hemorrhagic Shock

2 locations incl. Birmingham

Sponsor: Arsenal Medical, Inc.

Sex: All·Age: 15+

Code: NCT02880163·Recruiting

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A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

for Upper Urinary Tract Urothelial Carcinoma

23 locations incl. Homewood

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT06774131·Phase 3·Recruiting

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Improved Successful Retrieval Rate of HydroMARK Plus Breast Biopsy Site Marker in Comparison to HydroMARK as Well as Improved Surgeon Satisfaction

for Breast Neoplasm

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18 - 90

Code: NCT06294574·Recruiting

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Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Adolescents With Severe Alopecia Areata

for Alopecia Areata

54 locations incl. Birmingham

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 12 - 17

Code: NCT07133308·Phase 3·Recruiting

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A Study of Dotinurad Versus Allopurinol in Tophaceous Gout

for Tophaceous Gout

Drug: Dotinurad

86 locations incl. Birmingham

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07089888·Phase 3·Recruiting

Apply to this trial