Paid Clinical Trials in Alabama

Alabama has 1,359 paid clinical trials enrolling now across cities including Birmingham, Mobile and Huntsville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,359 clinical trials

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Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

for Peripheral Arterial Disease

Drug: Orforglipron

30 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07223593·Phase 3·Recruiting

Apply to this trial

Leading Healthy Eating and Activity Promotion Program

for Cancer Survivor

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT06868524·Recruiting

Apply to this trial

Retinal Detachment Prevention (Laser Prophylaxis) in Stickler Syndrome (SS)

for Stickler Syndrome Type 1

5 locations incl. Birmingham

Sponsor: Helen Keller Eye Research Foundation

Sex: All·Age: All ages

Code: NCT07146516·Recruiting

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A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis

for Bronchiectasis

14 locations incl. Mobile

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 85

Code: NCT07201051·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Bevacizumab

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701656·Phase 2·Recruiting

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Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

for Chronic Kidney Disease(CKD)

6 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06906627·Recruiting

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Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

for Chronic Kidney Disease(CKD)

6 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06906640·Recruiting

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The MIGHT Trial - An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing Myopathy

for Anti-3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR) Immune-Mediated Necrotizing Myopathy

5 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 16+

Code: NCT06599697·Phase 2·Recruiting

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Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

for Breast Cancer

12 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18 - 99

Code: NCT07211178·Recruiting

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ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy

for BAG3 Mutation Associated Dilated Cardiomyopathy

5 locations incl. Birmingham

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18 - 70

Code: NCT07218887·Phase 1, Phase 2·Recruiting

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Care in Multiple Sclerosis (MS)

for Multiple Sclerosis

6 locations incl. Birmingham

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07011914·Recruiting

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Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers

for Glaucoma

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT06629649·Recruiting

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Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

32 locations incl. Huntsville

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting

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A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

for Ovarian Neoplasms

82 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

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Pivotal Study of the Velocity™ pAVF System

for Chronic Kidney Disease

10 locations incl. Dothan

Sponsor: Venova Medical

Sex: All·Age: 18 - 80

Code: NCT07153939·Recruiting

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Proof of Concept Study to Assess the Pharmacokinetics/Pharmacodynamics of Nemolizumab in Adults With Chronic Pruritus of Unknown Origin (CPUO)

for Chronic Pruritus of Unknown Origin

Drug: Nemolizumab

25 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT07074977·Phase 2·Recruiting

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Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

for Atrial Fibrillation (AF)

35 locations incl. Dothan

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07175428·Phase 2·Recruiting

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Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

for Clonal Mast Cell Disease

18 locations incl. Birmingham

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT07143669·Recruiting

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A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

for Metabolic Dysfunction-Associated Steatotic Liver Disease

140 locations incl. Tuscaloosa

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07165028·Phase 3·Recruiting

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A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

for Alcohol Use Disorder

Drug: Brenipatide

30 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07219966·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients

for Knee Osteoarthritis

8 locations incl. Birmingham

Sponsor: Doron Therapeutics Inc.

Sex: All·Age: 40 - 80

Code: NCT07219771·Phase 3·Recruiting

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A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

for Non-small Cell Lung Cancer

Drug: Calderasib

9 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07190248·Phase 3·Recruiting

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A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Elranatamab

4 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT06988488·Phase 1, Phase 2·Recruiting

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Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis

for Proteinuria

Drug: Sparsentan

9 locations incl. Birmingham

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07219121·Phase 4·Recruiting

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Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC

for Metastatic Non-Squamous Non-Small Cell Lung Cancer

Drug: Nivolumab

4 locations incl. Birmingham

Sponsor: CatalYm GmbH

Sex: All·Age: 18+

Code: NCT07246863·Phase 2·Recruiting

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A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for Cachexia

Drug: ponsegromab

72 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06989437·Phase 2, Phase 3·Recruiting

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A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Auburn

Sponsor: Auburn University

Sex: All·Age: 19 - 65

Code: NCT05621538·Recruiting

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Legal Evaluation for Greater Access to Cancer Care (LEGAL-CARE)

for Cancer

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07197515·Recruiting

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The Effectiveness of a Proprietary Ashwagandha Extract on Menopausal Symptoms: A Three-Arm Randomized, Double-Blinded, Placebo Controlled Clinical Trial

for Menopausal Hot Flashes

1 location in Huntsville

Sponsor: Nutraceuticals Research Institute

Sex: Female·Age: 40 - 55

Code: NCT07210229·Not Yet Recruiting

Using TMS to Understand Neural Processes of Social Motivation

for Social Avoidant Behavior

1 location in Auburn

Sponsor: Auburn University

Sex: All·Age: 25 - 50

Code: NCT06274112·Recruiting

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A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

for Relapsed or Refractory Multiple Myeloma

10 locations incl. Birmingham

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18+

Code: NCT07116616·Phase 1, Phase 2·Recruiting

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Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty

for Pain

5 locations incl. Daphne

Sponsor: Synaptrix, Inc.

Sex: All·Age: 21+

Code: NCT07191067·Recruiting

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A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

for Urinary Incontinence,Stress

Drug: Orforglipron

21 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: Female·Age: 18+

Code: NCT07202884·Phase 3·Recruiting

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Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)

for Primary Membranous Nephropathy

22 locations incl. Montgomery

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 75

Code: NCT07204275·Phase 2, Phase 3·Recruiting

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A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

for Non-small Cell Carcinoma

133 locations incl. Alabaster

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07144280·Phase 3·Recruiting

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TLN-372 in Advanced KRAS Mutant Solid Tumors

for KRAS Mutant Solid Tumors

6 locations incl. Birmingham

Sponsor: Treeline Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07204340·Phase 1·Recruiting

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This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

for Metastatic Castration Sensitive Prostate Cancer (mCSPC)

Drug: Mevrometostat

120 locations incl. Huntsville

Sponsor: Pfizer

Sex: Male·Age: 18+

Code: NCT07028853·Phase 3·Recruiting

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A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza

for Influenza

120 locations incl. Anniston

Sponsor: Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Sex: All·Age: 12+

Code: NCT07159763·Phase 3·Recruiting

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A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

for Hypothalamic Obesity

8 locations incl. Birmingham

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 4+

Code: NCT06760546·Phase 3·Recruiting

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GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

for Aortic Dissection

16 locations incl. Birmingham

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06827990·Recruiting

Apply to this trial