KarXT Clinical Trials (2026): 25 Studies for Schizophrenia & Psychosis Associated With Alzheimer's Disease

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

25 KarXT clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 12 indications (including Schizophrenia & Psychosis Associated With Alzheimer's Disease) and 15,268 total planned enrollment. 17 Phase 3 KarXT trials are listed. 21 KarXT clinical trials are actively recruiting at 307 U.S. sites across 31 states. Most recent activity: NCT07228338 (Oct 2031).

Where to Participate: All KarXT Trial Sites in the U.S. (307 sites across 31 states)

Every actively recruiting KarXTtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
AZChandler Clinical Trials, LLCChandler85224NCT06585787Map
AZGilbert Neurology Partners - PLLC - AvacareGilbert85297NCT06585787Map
AZGilbert Neurology Partners/CCT ResearchGilbert85297NCT06947941Map
AZBanner Alzheimer's InstitutePhoenix85006-2528NCT06585787Map
AZImaging EndpointsScottsdale85258NCT06937229Map
AZScottsdale Clinical TrialsScottsdale85260-6742NCT06585787Map
ARPillar Clinical Research - BentonvilleBentonville72712NCT06951698Map
ARPillar Clinical Research - RichardsonBentonville72712NCT06929273Map
ARPillar Clinical Research- Little RockLittle Rock72204NCT06929273Map
ARPillar Clinical Research- Little RockLittle Rock72204NCT06951711Map
ARWoodland International Research GroupLittle Rock72211NCT06929273Map
ARWoodland International Research GroupLittle Rock72211NCT06951698Map
ARWoodland Research NorthwestRogers72758NCT06929273Map
ARWoodland Research NorthwestRogers72758NCT06951711Map
CAAdvanced Research Center Inc.Anaheim92805NCT06929273Map
CAAdvanced Research Center Inc.Anaheim92805NCT06951698Map
CAAdvanced Research Center Inc.Anaheim92805NCT07288567Map
CAAdvanced Research Center, Inc.Anaheim92805-5854NCT06585787Map
CAAdvanced Research Center, Inc.Anaheim92805-5854NCT05980949Map
CACITrialsBellflower90706NCT06951698Map
CAClinical Innovations, Inc. dba CITrialsBellflower90706NCT06929273Map
CAInland Psychiatric Medical Group - ChinoChino91710NCT06929273Map
CAInland Psychiatric Medical Group (IPMG)-ChinoChino91710NCT06585787Map
CAInland Psychiatric Medical Group.Chino91710NCT06947941Map
CAInland Psychiatric Medical Group.Chino91710NCT07288567Map
CAProscience Research GroupCulver City90230NCT06929273Map
CAProscience Research GroupCulver City90230NCT06951711Map
CAFullerton Neurology and Headache CenterFullerton92835NCT06976203Map
CACollaborative Neuroscience Research, LLCGarden Grove92845-2506NCT06929273Map
CAInglewood ClinicalInglewood90301NCT06976203Map
CAIrvine Clinical ResearchIrvine92614NCT06976203Map
CAOmega Clinical Trials - La HabraLa Habra90631NCT06929273Map
CACollaborative Neuroscience Research, LLCLong Beach90806NCT06951698Map
CAHealthy Brain ClinicLong Beach90804NCT06976216Map
CALong Beach Research Institute, LLCLong Beach90805NCT06585787Map
CACollaborative Neuroscience Research, LLCLos Alamitos90720-3118NCT07061288Map
CAUSC - The Memory and Aging Center (MAC) - Alzheimer Disease Research Center (ADRC)Los Angeles90033-5313NCT06585787Map
CAUSC - The Memory and Aging Center (MAC) - Alzheimer Disease Research Center (ADRC)Los Angeles90033-5313NCT05980949Map
CACatalina Research Institute, LLCMontclair91763NCT06929273Map
CACatalina Research Institute, LLCMontclair91763NCT06951698Map
CAATP Clinical Research-302 W La Veta AveOrange92866NCT05511363Map
CANRC Research InstituteOrange92868NCT06929273Map
CANRC Research InstituteOrange92868NCT06951698Map
CANRC Research Institute - Orange - PPDSOrange92868-2847NCT06585787Map
CASC3 Research - Pasadena - 960 E. Green StPasadena91106NCT06585787Map
CASC3 Research - Pasadena - 960 E. Green StPasadena91106NCT05980949Map
CAProspective Research Innovations 8577 Haven AveRancho Cucamonga91730NCT06585787Map
CAAnderson Clinical ResearchRedlands92374NCT06976216Map
CAClinical Innovations, Inc. dba CITrialsRiverside92506NCT06929273Map
CAClinical Innovations, Inc. dba CITrialsRiverside92506NCT06951711Map
CACollaborative Neuroscience Research, LLCTorrance90504NCT06929273Map
CACollaborative Neuroscience Research, LLCTorrance90502NCT06951711Map
CASunwise Clinical Research, LLC - Walnut Creek - IVY - PPDSWalnut Creek94596NCT05511363Map
CASunwise Clinical Research, LLC - Walnut Creek - IVY - PPDSWalnut Creek94596NCT05980949Map
COMountain Neurological Research CenterBasalt81621NCT06976216Map
COResearch of the RockiesColorado Springs80919NCT06976203Map
CTUniversity of Connecticut Health CenterFarmington06030NCT06585787Map
CTUniversity of Connecticut Health CenterFarmington06030NCT05980949Map
CTConnecticut Mental Health CenterNew Haven06519NCT06951698Map
CTYale New Haven Hospital-Smilow Cancer CenterNew Haven06510NCT06929273Map
DCGeorgetown University Medical CenterWashington D.C.20007NCT06976216Map
FLGenesis Trust Research GroupAtlantis33462NCT06585787Map
FLJEM Research InstituteAtlantis33462NCT06976216Map
FLVIN-Julie SchwartzbardAventura33180NCT06976216Map
FLEnvision Trials LLCBonita Springs34134NCT06585787Map
FLEnvision Trials LLCBonita Springs34134NCT05511363Map
FLEnvision Trials LLCBonita Springs34134NCT05980949Map
FLK2 Medical Research - Winter GardenClermont34711-5933NCT05511363Map
FLK2 Medical Research - Winter GardenClermont34711-5933NCT05980949Map
FLJY Research Institute IncCutler Bay33189-1230NCT06585787Map
FLJY Research Institute IncCutler Bay33189-1230NCT05980949Map
FLArrow Clinical TrialsDaytona Beach32117-5532NCT06585787Map
FLArrow Clinical TrialsDaytona Beach32117-5532NCT05511363Map
FLArrow Clinical TrialsDaytona Beach32117-5532NCT05980949Map
FLQuantum Laboratories, Inc - West Palm Beach OfficeDeerfield Beach33442NCT06585787Map
FLBetancourt Research ServicesDoral33172-2638NCT05980949Map
FLIntegrity Clinical Research LLC - 21st StreetDoral33122-1620NCT06585787Map
FLIntegrity Clinical Research LLC - 21st StreetDoral33122-1620NCT05980949Map
FLNeuropsychiatric Research Center of Southwest FloridaFort Myers33912NCT06976203Map
FLVelocity Clinical Research, Hallandale BeachHallandale33009NCT06929273Map
FLDirect Helpers Research CenterHialeah33012-3618NCT05980949Map
FLGaliz ResearchHialeah33016-1814NCT05980949Map
FLLas Mercedes Medical Research - 4440 West 16th AveHialeah33012NCT05980949Map
FLNew Life Medical Research Center -3750 W 16th AveHialeah33012-4648NCT06585787Map
FLNew Life Medical Research Center -3750 W 16th AveHialeah33012-4648NCT05980949Map
FLResearch in Miami, IncHialeah33013NCT06585787Map
FLBehavioral Clinical ResearchHollywood33021NCT06929273Map
FLBehavioral Clinical ResearchHollywood33021NCT06951711Map
FLResearch Centers of America ( Hollywood )Hollywood33024NCT06929273Map
FLResearch Centers of America ( Hollywood )Hollywood33024NCT06951698Map
FLResearch Centers of America ( Hollywood )Hollywood33024NCT07061288Map
FLAdvanced Research Institute of MiamiHomestead33033NCT06951698Map
FLCoral Clinic ResearchHomestead33032NCT05980949Map
FLHomestead Associates in Research Inc-30328 Old Dixie HwyHomestead33033NCT05980949Map
FLNexus Clinical Research Center- NRCHomestead33030NCT06585787Map
FLNexus Clinical Research Center- NRCHomestead33030NCT05980949Map
FLJacksonville Center for Clinical ResearchJacksonville32216NCT06976203Map
FLK2 Medical Research - Lady LakeLady Lake32159NCT06585787Map
FLK2 MEDICAL Research THE VILLAGESLady Lake32159NCT06976203Map
FLK2 Medical Research - MaitlandMaitland32751-5669NCT05511363Map
FLK2 Medical Research - MaitlandMaitland32751-5669NCT05980949Map
FLMerritt Island Medical Research, LLCMerritt Island32952NCT06976216Map
FLA & D Doctor CenterMiami33135-2968NCT06585787Map
FLA & D Doctor CenterMiami33135-2968NCT05980949Map
FLAdvanced Research Institute of MiamiMiami33135NCT06929273Map
FLAllied Biomedical Research InstituteMiami33155-4630NCT05980949Map
FLAngels Clinical Research Institute - MiamiMiami33122-1721NCT05980949Map
FLBanyan Behavioal Care Program - CSUMiami33134NCT07379827Map
FLCCM Clinical Research GroupMiami33133-4231NCT05980949Map
FLCoral Research Clinic & Coral Diagnostic CenterMiami33186-4643NCT05980949Map
FLDade Research Center - Miami FL - 7600 SW 87th AveMiami33173NCT06585787Map
FLDade Research Center - Miami FL - 7600 SW 87th AveMiami33173NCT05980949Map
FLFlorida Research Center, Inc.Miami33174-2950NCT05980949Map
FLFloridian Neuroscience Institute-1901 SW 1 StMiami33135NCT06585787Map
FLFloridian Neuroscience Institute-1901 SW 1 StMiami33135NCT05980949Map
FLFuture Care Solution LLCMiami33165-3947NCT06585787Map
FLFuture Care Solution LLCMiami33165-3947NCT05980949Map
FLHigh Quality ResearchMiami33184-1412NCT06585787Map
FLHigh Quality ResearchMiami33184-1412NCT05980949Map
FLHomestead Associates in Research IncMiami33032NCT06585787Map
FLIMIC LLC- 9380 SW 150th StrMiami33176-7947NCT06585787Map
FLIMIC LLC- 9380 SW 150th StrMiami33176-7947NCT05980949Map
FLLCC Medical Research InstituteMiami33126NCT06929273Map
FLLCC Medical Research InstituteMiami33126NCT06951711Map
FLMedOne Clinical Research LLCMiami33145-2455NCT05980949Map
FLMiami Jewish Health SystemsMiami33137NCT06585787Map
FLMy Community Research Center, Inc - 7480 Bird RdMiami33155-6630NCT06585787Map
FLMy Community Research Center, Inc - 7480 Bird RdMiami33155-6630NCT05980949Map
FLNew Gen HealthMiami33176NCT06585787Map
FLNew Gen HealthMiami33176NCT05980949Map
FLNovel Clinical Research Center, LLC -7000 SW 97th AveMiami33173-1474NCT05980949Map
FLNovel Clinical Research Center, LLC.Miami33173-1474NCT06585787Map
FLNuovida Research CenterMiami33186NCT06937229Map
FLONHEALTH Research CenterMiami33186-5882NCT05980949Map
FLPremier Clinical Research InstituteMiami33122-1335NCT06585787Map
FLPremier Clinical Research InstituteMiami33122-1335NCT05980949Map
FLReliant Medical ResearchMiami33165NCT06585787Map
FLReliant Medical ResearchMiami33165NCT05980949Map
FLSerenity Research CenterMiami33176-1451NCT06585787Map
FLSerenity Research CenterMiami33176-1451NCT05980949Map
FLSouth Florida Research Phase I-IVMiami33166NCT06951698Map
FLSouth Florida Research Phase I-IV, Inc. - MiamiMiami33166NCT05980949Map
FLWellness Research Center Inc - MiamiMiami33135-1601NCT06585787Map
FLWellness Research Center Inc - MiamiMiami33135-1601NCT05980949Map
FLNew Med ResearchMiami Gardens33056-4000NCT06585787Map
FLNew Med ResearchMiami Gardens33056-4000NCT05980949Map
FLAngels Clinical Research Institute - Miami Lakes - Palm Springs - PPDSMiami Lakes33016NCT06585787Map
FLInnovative Clinical Research, Inc.Miami Lakes33016NCT06929273Map
FLInnovative Clinical Research, Inc.Miami Lakes33016NCT06951698Map
FLInnovative Clinical Research, Inc.Miami Lakes33016NCT06951711Map
FLInnovative Clinical Research, Inc.Miami Lakes33016NCT07061288Map
FLMeridian International ResearchMiami Lakes33014-6435NCT05980949Map
FLPanax Clinical ResearchMiami Lakes33014NCT06585787Map
FLSan Marcus Research Clinic IncMiami Lakes33014-5602NCT05980949Map
FLOcean Blue Medical Research Center IncMiami Springs33166-5260NCT05980949Map
FLSouth Florida Research Phase I-IVMiami Springs33166NCT06929273Map
FLSouth Florida Research Phase I-IVMiami Springs33166NCT06951711Map
FLAqualane Clinical ResearchNaples34105NCT06585787Map
FLRenstar Medical ResearchOcala34470NCT06976216Map
FLSensible HealthCare, LLCOcoee34761-2964NCT06585787Map
FLApg Research, LlcOrlando32803NCT07288567Map
FLApg Research, LlcOrlando32803NCT07424404Map
FLCombined Research Orlando Phase I-IV LLCOrlando32807-3555NCT06585787Map
FLCombined Research Orlando Phase I-IV LLCOrlando32807-3555NCT05980949Map
FLNova PsychiatryOrlando32803NCT06585787Map
FLNova PsychiatryOrlando32803NCT05980949Map
FLNeurology Associates of Ormond BeachOrmond Beach32174-3101NCT06585787Map
FLNeurology Associates of Ormond BeachOrmond Beach32174-3101NCT05980949Map
FLProgressive Medical ResearchPort Orange32127NCT06937229Map
FLProgressive Medical Research (Duplicate)Port Orange32127NCT06585787Map
FLIntercoastal Medical GroupSarasota34239NCT06976203Map
FLAlzheimer's Research and Treatment CenterStuart34997NCT06976216Map
FLHealth Synergy Clinical Research,LLC - StuartStuart34994NCT06126224Map
FLCordova Research Institute- SweetwaterSweetwater33182NCT06585787Map
FLAngels Clinical Research Institute Tampa - Palm Springs - PPDSTampa33614-2869NCT06585787Map
FLAngels Clinical Research Institute Tampa - Palm Springs - PPDSTampa33614-2869NCT05980949Map
FLGuardian Angel ResearchTampa33614NCT06585787Map
FLGuardian Angel ResearchTampa33614NCT05980949Map
FLInterventional Psychiatry of Tampa BayTampa33629-5837NCT06585787Map
FLInterventional Psychiatry of Tampa BayTampa33629-5837NCT05980949Map
FLIPTB Clinical ResearchTampa33629NCT06937229Map
FLUniversity of South FloridaTampa33606NCT05511363Map
FLUSF Health Byrd Alzheimer's InstituteTampa33613NCT06976203Map
FLCharter Research - Lady LakeThe Villages32162NCT06976216Map
FLLocal Institution - 1131Viera32940NCT06126224Map
FLHope Research Network - MiamiVirginia Gardens33166NCT06937229Map
FLAlzheimer's Research and Treatment CenterWellington33414NCT06976203Map
FLHealth Synergy Clinical ResearchWest Palm Beach33407NCT06929273Map
FLHealth Synergy Clinical ResearchWest Palm Beach33407NCT06951698Map
FLHealth Synergy Clinical ResearchWest Palm Beach33407NCT06951711Map
FLPremiere Research Institute at Palm Beach Neurology, PAWest Palm Beach33407-3209NCT06585787Map
FLPremiere Research Institute at Palm Beach Neurology, PAWest Palm Beach33407-3209NCT05980949Map
GAAgile Clinical Research Trials, LLCAtlanta30328-5532NCT06585787Map
GAAgile Clinical Research Trials, LLCAtlanta30328-5532NCT05980949Map
GAAtlanta Center for Medical ResearchAtlanta30331NCT06929273Map
GAAtlanta Center for Medical ResearchAtlanta30331NCT06951711Map
GAAtlanta Center for Medical ResearchAtlanta30331NCT07061288Map
GAAtlanta Center for Medical ResearchAtlanta30331NCT07288567Map
GAAtlanta Center for Medical ResearchAtlanta30331NCT07424404Map
GASynexus Clinical Research US, Inc.Atlanta30328NCT06929273Map
GASynexus Clinical Research US, Inc.Atlanta30328NCT06951698Map
GACenExel iResearch, LLCDecatur30030NCT06929273Map
GACenExel iResearch, LLCDecatur30030NCT06951711Map
GACenExel iResearch, LLCDecatur30030NCT07061288Map
GACenter for Advanced Research & EducationGainesville30501NCT06976216Map
GASalveo Integrative Health - LawrencevilleLawrenceville30046NCT07288567Map
GASalveo Integrative Health - LawrencevilleLawrenceville30046NCT07424404Map
GACenExel iResearch, LLCSavannah31405NCT06929273Map
GACenExel iResearch, LLCSavannah31405NCT06951698Map
GADenali Health Atlanta, LLCStone Mountain30083NCT07288567Map
ILEmVenio Research Center - Prime HealthcareChicago60622NCT07288567Map
ILEmVenio Research Center - Prime HealthcareChicago60622NCT07424404Map
ILGreat Lakes Clinical Trials - AndersonvilleChicago60640NCT06976203Map
ILPillar Clinical Research -ChicagoChicago60641NCT06929273Map
ILPillar Clinical Research -ChicagoChicago60641NCT06951698Map
ILRe:Cognition Health - ChicagoChicago60611NCT06976216Map
ILUptown Research InstituteChicago60640NCT07061288Map
ILAscension Alexian BrothersElk Grove Village60007NCT06976216Map
ILSouthern Illinois University School of MedicineSpringfield62702NCT06976203Map
INJosephson Wallack Munshower Neurology, PCIndianapolis46256NCT06976203Map
KSICON - LenexaLenexa66219-9746NCT07118215Map
MDCBH HealthGaithersburg20877NCT06929273Map
MDCBH HealthGaithersburg20877NCT06951711Map
MAMcLean HospitalBelmont02478-1064NCT06585787Map
MATufts Medical Center - 800 Washington St - PPDSBoston02111-1552NCT06585787Map
MABoston Center for MemoryNewton02459NCT06937229Map
MABoston Center for MemoryNewton02459NCT06976216Map
MABoston Neuro Research CenterNorth Dartmouth02747-2612NCT06585787Map
MAElixia Health - Springfield - Elixia - PPDSSpringfield01103NCT06585787Map
MINeurobehavioral Medicine Group (NBMG)Bloomfield Township48302-1909NCT06585787Map
MIQUEST Research InstituteFarmington Hills48334NCT06976203Map
MNHealthPartners Neuroscience CenterSaint Paul55130NCT06976216Map
MSPrecise Research CentersFlowood39232NCT06585787Map
MSPrecise Research CentersFlowood39232NCT05980949Map
MSPrecise Research CentersFlowood39232NCT06929273Map
MSPrecise Research CentersFlowood39232NCT06951711Map
MSPrivate Practice - Dr. Ronald Louis SchwartzHattiesburg39401NCT06976203Map
MOArch Clinical TrialsSt Louis63141NCT06929273Map
MOArch Clinical TrialsSt Louis63141NCT06951711Map
NVRedbird ResearchLas Vegas89119NCT06937229Map
NJHassman Research Institute Marlton SiteMarlton08053NCT06929273Map
NJHassman Research Institute Marlton SiteMarlton08053NCT06951711Map
NJHassman Research Institute Marlton SiteMarlton08053NCT07061288Map
NJThe Cognitive and Research Center of New JerseySpringfield07081NCT06976203Map
NJAdvanced Memory Research Institute - CenExel - PPDSToms River08755NCT06585787Map
NJAdvanced Memory Research Institute of New JerseyToms River08755NCT06976216Map
NJBio Behavioral HealthToms River08755NCT06585787Map
NJAdvanced Clinical InstituteWest Long Branch07764NCT06976203Map
NYNeurological Associates AlbanyAlbany12208NCT06976203Map
NYDent Neurosciences Research Center, IncAmherst14226NCT06976203Map
NYUniversity at Buffalo - UBMD NeurologyBuffalo14203NCT06976203Map
NYNYU Langone HealthNew York10016NCT06976216Map
NYRichmond Behavioral AssociatesStaten Island10314NCT06929273Map
NYRichmond Behavioral AssociatesStaten Island10314NCT06951698Map
NYSUNY Upstate Medical UniversitySyracuse13210NCT06976216Map
NYFive Towns Neurology PC -Woodmere - 923 BroadwayWoodmere11598-1739NCT05980949Map
NYFive Towns Neurology, PCWoodmere11598-1739NCT06585787Map
NYFive Towns Neurology, PCWoodmere11598-1739NCT05511363Map
NCTriad Clinical Trials - 515 College RdGreensboro27410-3311NCT06585787Map
NCAMC Research, LLCMatthews28105NCT06976216Map
NCAMC Research, LLC - Flourish - PPDSMatthews28105-8336NCT06585787Map
NCAMC Research, LLC - Flourish - PPDSMatthews28105-8336NCT05980949Map
NCWest Clinical ResearchMorehead City28557NCT06585787Map
NCWest Clinical ResearchMorehead City28557NCT06937229Map
NCPPD Virtual - PPD - USWilmington28401-3331NCT07379827Map
OHUniversity of Cincinnati Cancer InstituteCincinnati45219NCT07424404Map
OHUniversity of Cincinnati Dept of Psychiatry and Behavioral NeuroscienceCincinnati45219NCT07288567Map
OHUniversity of Cincinnati Medical CenterCincinnati45219NCT06929273Map
OHUniversity of Cincinnati Medical CenterCincinnati45219NCT06951711Map
OHOhio State UniversityColumbus43221NCT06585787Map
OHOhio State UniversityColumbus43221NCT06976216Map
OHNDx Clinical Research Inc.Dayton45459NCT06976216Map
OHInsight Clinical Trials LLC - IndependenceIndependence44131NCT06585787Map
OHNeuro-Behavioral Clinical ResearchNorth Canton44720NCT06929273Map
OHNeuro-Behavioral Clinical ResearchNorth Canton44720NCT06951698Map
OHNeuro-Behavioral Clinical ResearchNorth Canton44720NCT06951711Map
OKThe Rivus Wellness & Research InstituteOklahoma City73112NCT06585787Map
ORSummit HeadlandsPortland97210NCT06976216Map
PAKeystone Clinical StudiesPlymouth Meeting19462NCT06976203Map
RIRhode Island Mood & Memory Research InstituteEast Providence02914NCT06976216Map
RIAlzheimer's Disease and Memory Disorders Center at Rhode Island HospitalProvidence02903NCT06585787Map
TNNeurology Clinic, P.C.Cordova38018NCT06976216Map
TNPsychiatric Consultants, PcFranklin37607NCT07379827Map
TNVanderbilt Psychiatric HospitalNashville37212-3133NCT06585787Map
TXCommunity Clinical ResearchAustin78754NCT06929273Map
TXCommunity Clinical ResearchAustin78754NCT07061288Map
TXGadolin ResearchBeaumont77702NCT06976216Map
TXEpic Medical Research, LLC - CarroltonCarrollton75006NCT06937229Map
TXHorizon Clinical Research: Gill NeuroscienceCypress77429-6070NCT05980949Map
TXLocal Institution - 1106Cypress77429-6070NCT06126224Map
TXEpic Medical Research LLC - DeSoto - HyperCore - PPDSDeSoto75115-2043NCT06585787Map
TXInSite Clinical ResearchDeSoto75115NCT06929273Map
TXInSite Clinical ResearchDeSoto75115NCT06951711Map
TXAdvanced Neuro Research Center - El PasoEl Paso79912-1743NCT06585787Map
TXClinical Trial Network - 7080 Southwest FwyHouston77074-2085NCT05511363Map
TXClinical Trial Network - 7080 Southwest FwyHouston77074-2085NCT05980949Map
TXElevate Clinical Research-HoustonHouston77058NCT06929273Map
TXPrime Clinical Research - MansfieldMansfield76063NCT06929273Map
TXAIM TrialsPlano75093-8225NCT06585787Map
TXPillar Clinical Research - RichardsonRichardson75080NCT06929273Map
TXPillar Clinical Research - RichardsonRichardson75080NCT06951698Map
TXPillar Clinical Research - RichardsonRichardson75080NCT06951711Map
TXCentral Texas Neurology Consultants, PARound Rock78681NCT06976203Map
TXGlenn Biggs Institute for Alzheimer's & Neurodegenerative DiseasesSan Antonio78229-3901NCT06585787Map
UTPantheon Clinical Research, LLCBountiful84010NCT06937229Map
VAConquest Research, LLC - Virginia - ViennaVienna22182NCT06585787Map
WARainier Clinical Research CenterRenton98057NCT06976203Map

KarXT clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingcompletednot yet recruitingTotal
Early P111
P1224
P1/P211
P3141217
N/A112

Recruiting KarXT clinical trials (21)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT07228338Cholinergic Enhancement of ThetaEarly P1Epilepsy50Oct 2026
NCT07424404A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, RespectivelyP3Schizophrenia400Apr 2026
NCT07288567EMERGENT TEENA Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)P3Schizophrenia166Jan 2026
NCT06882785A Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult Participants With SchizophreniaP3Schizophrenia250Jun 2025
NCT07285798A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum DisorderP3Irritability Associated With Autism Spectrum Disorder176Sep 2026
NCT06937229ADAGIO-3A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)P3Alzheimer Disease600Dec 2025
NCT07284745A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With AutismP3Irritability Associated With Autism Spectrum Disorder176Sep 2026
NCT06976203MINDSET 2A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)P3Alzheimer's Disease586Jul 2025
NCT06976216MINDSET 1A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's DiseaseP3Alzheimer's Disease586Jul 2025
NCT07379827Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)Schizophrenia1,500Feb 2026
NCT06929273BALSAM-3A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)P3Bipolar Disorder Type I With Mania450Jul 2025
NCT06947941ADEPT-5A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)P3Alzheimer Disease325Mar 2026
NCT07423546A PET/MRI Study of Cobenfy on Dopamine Transmission in SchizophreniaP1/P2SCHIZOPHRENIA 1 (Disorder)12Jul 2026
NCT07061288A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXTP1Schizophrenia116Sep 2025
NCT05980949ADEPT-3Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)P3Psychosis Associated With Alzheimer's Disease800Jul 2023
NCT06585787ADEPT-4A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)P3Alzheimer Disease406Sep 2024
NCT06126224ADEPT-2A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)P3Psychosis Associated With Alzheimer's Disease500Aug 2023
NCT06951711BALSAM-2A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)P3Bipolar Disorder Type I With Mania or Mania With Mixed Features274Jun 2025
NCT06951698BALSAM-1A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I DisorderP3Bipolar-I Disorder With Mania or Mania With Mixed Features274Jun 2025
NCT05511363ADEPT-1A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)P3Psychosis Associated With Alzheimer's Disease410Aug 2022
NCT07118215A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine, and DigoxinP1Healthy Volunteers60Sep 2025

KarXT clinical trials by indication

Schizophrenia (7)

NCTAcronymPhaseStatusTitle
NCT07424404P3recruitingA Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively
NCT07288567EMERGENT TEENP3recruitingA Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
NCT06882785P3recruitingA Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult Participants With Schizophrenia
NCT07379827N/ArecruitingEffectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
NCT07061288P1recruitingA Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT
NCT07571148N/Aactive not recruitingReal-world Patient Characteristics, Treatment Patterns, and Healthcare Utilization Among KarXT Users
NCT06572449P3completedStudy to Assess Safety and Effectiveness of Slowly Increasing Dose and Food Effect of KarXT in Participants With Schizophrenia

Alzheimer Disease (3)

NCTAcronymPhaseStatusTitle
NCT06937229ADAGIO-3P3recruitingA Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
NCT06947941ADEPT-5P3recruitingA Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
NCT06585787ADEPT-4P3recruitingA Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

Psychosis Associated With Alzheimer's Disease (3)

NCTAcronymPhaseStatusTitle
NCT05980949ADEPT-3P3recruitingOpen-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
NCT06126224ADEPT-2P3recruitingA Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
NCT05511363ADEPT-1P3recruitingA Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

Irritability Associated With Autism Spectrum Disorder (2)

NCTAcronymPhaseStatusTitle
NCT07285798P3not yet recruitingA Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder
NCT07284745P3not yet recruitingA Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism

Healthy Volunteers (2)

NCTAcronymPhaseStatusTitle
NCT07118215P1recruitingA Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine, and Digoxin
NCT06605950PKP1completedA Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of Xanomeline With Trospium Chloride Versus KarXT in Healthy Adult and Elderly Participants of Japanese Ethnicity and to Assess the Effect of Omeprazole on the PK of Xanomeline With Trospium Chloride in Healthy Adult Participants

Alzheimer's Disease (2)

NCTAcronymPhaseStatusTitle
NCT06976203MINDSET 2P3recruitingA Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
NCT06976216MINDSET 1P3recruitingA Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Epilepsy (1)

NCTAcronymPhaseStatusTitle
NCT07228338Early P1not yet recruitingCholinergic Enhancement of Theta

SCHIZOPHRENIA 1 (Disorder) (1)

NCTAcronymPhaseStatusTitle
NCT07423546P1/P2not yet recruitingA PET/MRI Study of Cobenfy on Dopamine Transmission in Schizophrenia

Bipolar Disorder Type I With Mania (1)

NCTAcronymPhaseStatusTitle
NCT06929273BALSAM-3P3recruitingA Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

Bipolar Disorder Type I With Mania or Mania With Mixed Features (1)

NCTAcronymPhaseStatusTitle
NCT06951711BALSAM-2P3recruitingA Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)

Bipolar-I Disorder With Mania or Mania With Mixed Features (1)

NCTAcronymPhaseStatusTitle
NCT06951698BALSAM-1P3recruitingA Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

Psychiatric Disorders (1)

NCTAcronymPhaseStatusTitle
NCT06853171P1completedSafety, Tolerability, and Pharmacokinetics of KarXT and Dual-burst Release of Xanomeline With Immediate-release Trospium Chloride in Adolescents With Psychiatric Disorders

KarXT pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
EMERGENT TEENNCT07288567P3recruitingSchizophrenia166
ADAGIO-3NCT06937229P3recruitingAlzheimer Disease600
MINDSET 2NCT06976203P3recruitingAlzheimer's Disease586
MINDSET 1NCT06976216P3recruitingAlzheimer's Disease586
BALSAM-3NCT06929273P3recruitingBipolar Disorder Type I With Mania450
ADEPT-5NCT06947941P3recruitingAlzheimer Disease325
ADEPT-3NCT05980949P3recruitingPsychosis Associated With Alzheimer's Disease800
ADEPT-4NCT06585787P3recruitingAlzheimer Disease406
ADEPT-2NCT06126224P3recruitingPsychosis Associated With Alzheimer's Disease500
BALSAM-2NCT06951711P3recruitingBipolar Disorder Type I With Mania or Mania With Mixed Features274
BALSAM-1NCT06951698P3recruitingBipolar-I Disorder With Mania or Mania With Mixed Features274
ADEPT-1NCT05511363P3recruitingPsychosis Associated With Alzheimer's Disease410

All KarXT trials (25)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT07228338Cholinergic Enhancement of ThetaEarly P1not yet recruiting50University of Texas Southwestern Medical CenterOct 2026
NCT07424404A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, RespectivelyP3recruiting400Karuna Therapeutics, Inc., a Bristol Myers Squibb companyApr 2026
NCT07288567EMERGENT TEENA Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)P3recruiting166Bristol-Myers SquibbJan 2026
NCT06882785A Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult Participants With SchizophreniaP3recruiting250Bristol-Myers SquibbJun 2025
NCT07285798A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum DisorderP3not yet recruiting176Bristol-Myers SquibbSep 2026
NCT06937229ADAGIO-3A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)P3recruiting600Bristol-Myers SquibbDec 2025
NCT07284745A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With AutismP3not yet recruiting176Bristol-Myers SquibbSep 2026
NCT06976203MINDSET 2A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)P3recruiting586Bristol-Myers SquibbJul 2025
NCT06976216MINDSET 1A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's DiseaseP3recruiting586Bristol-Myers SquibbJul 2025
NCT07379827Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)recruiting1,500Bristol-Myers SquibbFeb 2026
NCT06929273BALSAM-3A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)P3recruiting450Bristol-Myers SquibbJul 2025
NCT06947941ADEPT-5A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)P3recruiting325Bristol-Myers SquibbMar 2026
NCT07423546A PET/MRI Study of Cobenfy on Dopamine Transmission in SchizophreniaP1/P2not yet recruiting12New York State Psychiatric InstituteJul 2026
NCT07061288A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXTP1recruiting116Bristol-Myers SquibbSep 2025
NCT05980949ADEPT-3Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)P3recruiting800Karuna Therapeutics, Inc., a Bristol Myers Squibb companyJul 2023
NCT06585787ADEPT-4A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)P3recruiting406Karuna Therapeutics, Inc., a Bristol Myers Squibb companySep 2024
NCT06126224ADEPT-2A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)P3recruiting500Karuna Therapeutics, Inc., a Bristol Myers Squibb companyAug 2023
NCT06951711BALSAM-2A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)P3recruiting274Bristol-Myers SquibbJun 2025
NCT06951698BALSAM-1A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I DisorderP3recruiting274Bristol-Myers SquibbJun 2025
NCT05511363ADEPT-1A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)P3recruiting410Karuna Therapeutics, Inc., a Bristol Myers Squibb companyAug 2022
NCT07571148Real-world Patient Characteristics, Treatment Patterns, and Healthcare Utilization Among KarXT Usersactive not recruiting6,876Bristol-Myers SquibbJan 2026
NCT07118215A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine, and DigoxinP1recruiting60Karuna Therapeutics, Inc., a Bristol Myers Squibb companySep 2025
NCT06853171Safety, Tolerability, and Pharmacokinetics of KarXT and Dual-burst Release of Xanomeline With Immediate-release Trospium Chloride in Adolescents With Psychiatric DisordersP1completed24Bristol-Myers SquibbApr 2025
NCT06605950PKA Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of Xanomeline With Trospium Chloride Versus KarXT in Healthy Adult and Elderly Participants of Japanese Ethnicity and to Assess the Effect of Omeprazole on the PK of Xanomeline With Trospium Chloride in Healthy Adult ParticipantsP1completed78Karuna Therapeutics, Inc., a Bristol Myers Squibb companyOct 2024
NCT06572449Study to Assess Safety and Effectiveness of Slowly Increasing Dose and Food Effect of KarXT in Participants With SchizophreniaP3completed173Karuna Therapeutics, Inc., a Bristol Myers Squibb companyOct 2024

KarXT clinical trials: frequently asked questions

How many KarXT clinical trials are there?
25 KarXT clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 17 are actively recruiting participants. 3 are marked completed.
Are KarXT clinical trials recruiting in 2026?
Yes — 17 KarXT trials are actively recruiting in 2026, with 307 U.S. sites across 31 states. See the recruiting trials and the per-state site list further down this page.
What conditions is KarXT being studied for?
KarXT is being studied for Schizophrenia, Psychosis Associated With Alzheimer's Disease, Alzheimer Disease, Irritability Associated With Autism Spectrum Disorder, Alzheimer's Disease and 15 more. The trials are grouped by indication on this page.
What phase is KarXT in?
KarXT clinical trials span 17 Phase 3, 4 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors KarXT clinical trials?
The lead sponsor across the most KarXT trials is Bristol-Myers Squibb, with 3 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming KarXTas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed .

Related pages on Hipa.ai: