Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity

Sponsor
Radboud University Medical Center
Study ID
NCT07504172
Status
Not Yet Recruiting

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Conditions

  • Obesity (Disorder)
  • Overweight , Obesity

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tirzepatide — DRUG
    Initiating treatment with tirzepatide

Study Details

Tirzepatide is one of the new medications for the treatment of obesity. In clinical research people treated with Tirzepatide have weight loss up to 21%. But there is only a little bit of research showing the effect of Tirzepatide in clinical practice. In this retrospective observational study the investigators will evaluate the effectiveness of tirzepatide in routine clinical practice among adults with obesity in the Netherlands.The main questions it aims to answer are: * How much weight do patients lose after six months of treatment with tirzepatide combined with lifestyle coaching? * How is the medication dosed in daily practice? Researchers will use data from electronic health records of patients in multiple outpatient locations of the Dutch Obesity Clinic (NOK, Nederlandse Obesitas Kliniek).

Key Dates

Start date
Apr 1, 2026
Status verified
Feb 2026
Primary completion
Jul 1, 2026
Completion
Aug 1, 2026

Study Design

Enrollment
1,700 participants (estimated)

Arms

  • Arm: People with obesity
    Adults

Primary Outcome Measure

Weight change [ Time Frame: Baseline-6 months ]

Central Contacts

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