The Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity

Part of paid clinical trials in Jackson, Mississippi.

Sponsor
University of Mississippi Medical Center
Study ID
NCT07052539
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Accepted

Interventions

  • High protein and sodium meal — OTHER
    Meal with 1g/kg protein content and 3900mg sodium

Study Details

This research study wants to learn about Chronic Kidney Disease (CKD) with Obesity, and Heart Failure with preserved Ejection Fraction (HFpEF) and better ways to evaluate these diseases. HFpEF means that the heart is not able to fill properly with blood while it is resting so the amount of blood pumped out to the body is less than it would be if it was filling properly. The study is being done to describe the differences in how the kidneys handle protein and salt in participants with HFpEF and obesity compared to healthy persons.

Key Dates

Start date
Jul 22, 2022
Status verified
Jun 2025
Primary completion
Jun 30, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
60 participants (estimated)

Arms

  • Arm: Healthy Participants
  • Arm: Obese Participants without HFpEF
  • Arm: HFpEF and Obese Participants

Primary Outcome Measure

Change in measured GFR [ Time Frame: 5 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Mississippi Medical CenterJacksonMississippi39216
Tekka Johnson
[email protected]
601-496-7834
Marissa C Tio, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Jackson, MS

By condition
Chronic kidney disease
By specialty
NephrologyKidney disease
By research site
University of Mississippi Medical Center· Jackson, MS

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