Efficacy of Intravenous Oxytocin to Speed Recovery After THA

Part of paid clinical trials in Winston-Salem, North Carolina.

Sponsor
Wake Forest University Health Sciences
Study ID
NCT07430228
Phase
PHASE2
Status
Enrolling By Invitation

Conditions

  • Total Hip Arthroplasty

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • intravenous administration of oxytocin — DRUG
    Single administration of oxytocin 26 micrograms administered intravenously over a period of 45 minutes.
  • Placebo — DRUG
    Saline will be administered intravenously over a period of 45 minutes

Study Details

The purpose of this study is to test whether perioperative intravenous (IV) oxytocin compared to placebo results in faster recovery in disability as measured by daily steps over 56 days after Total Hip Arthroplasty (THA).

Key Dates

Start date
Jun 30, 2026
Status verified
May 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
80 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Oxytocin
    Oxytocin 26 micrograms administered intravenously
  • Placebo Comparator: Placebo
    Placebo administered intravenously

Primary Outcome Measure

Modeled daily steps trajectory [ Time Frame: 56 days after surgery ]

Locations (1)

FacilityCityStateZIPSite coordinators
Atrium Health Wake Forest BaptistWinston-SalemNorth Carolina27157-

Find similar trials in Winston-Salem, NC

By research site
Atrium Health Wake Forest Baptist· Winston-Salem, NC

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