Assessing the Feasibility of Multi-modal Biosensing for Monitoring Mobility and Cognition in Older Adults

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Tufts University
Study ID
NCT07217951
Status
Not Yet Recruiting

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Conditions

  • Chronic Stress
  • Mobility and Independence
  • Systemic Inflammation

Eligibility Criteria

Sex
ALL
Age
65 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Eutectogel Sensors and Microneedle Patches — DEVICE
    Eutectogel Sensors: While the exact eutectogel formulation in this study has not been previously tested in humans, similar eutectogel-based materials have been employed in wearable biosensing devices with human participants. These systems are typically composed of biocompatible matrices such as gelatin or polyacrylamide combined with deep eutectic solvents (DES) to improve ionic conductivity and flexibility. Microneedle Patches: The microneedle patch in this study is composed of poly(acrylic acid)/gelatin methacryloyl (PAA/GelMA), gelatin/oxidized pectin (Gelatin/OxP), and methacrylated hyaluronic acid/maleic anhydride (MeHA/MA). Although the integrated use of these specific compositions has not yet been evaluated in humans, the materials themselves, as well as similar microneedle architectures, have been thoroughly investigated in vivo and even in clinical trials.

Study Details

Current health devices often overlook older users, who may face both health challenges and technology barriers. We are investigating the feasibility of wearable sensors to track posture, heart rate, and breathing, alongside a microneedle patch that collect body fluids to measure stress and inflammation markers. By combining this data, we aim to create an easy to use system that supports personalized, at home health monitoring for older adults.

Key Dates

Start date
Dec 31, 2025
Status verified
Oct 2025
Primary completion
Sep 30, 2028
Completion
Sep 30, 2028

Study Design

Enrollment
20 participants (estimated)

Arms

  • Arm: Older adults
    Adults aged 65 or older

Primary Outcome Measure

Subtle biomechanical signals and interstitial fluid with key biomarkers. [ Time Frame: From enrollment to end of study period at 8 days. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Jean Mayer USDA Human Nutrition Research Center on AgingBostonMassachusetts02111-

Find similar trials in Boston, MA

By research site
Jean Mayer USDA Human Nutrition Research Center on Aging· Boston, MA

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