Effects of HIIT vs. TRE on Type 2 Diabetes Risk

Part of paid clinical trials in Syracuse, New York.

Sponsor
Syracuse University
Study ID
NCT07215533
Status
Recruiting
Apply to this trial

Conditions

  • High-intensity Interval Training
  • Metabolic Diseases
  • Obesity and Type 2 Diabetes
  • Time-restricted Eating

Eligibility Criteria

Sex
ALL
Age
14 Years - 30 Years
Healthy Volunteers
Accepted

Interventions

  • High-intensity interval training — BEHAVIORAL
    The 4-week HIIT intervention will use a stationary bicycle performed 3 times/week (a total of 12 sessions over the 4-week), performing at the CRL. All participants will perform a 20-minute HIIT protocol (20 repetitions of 10-seconds work time followed by 50-seconds resting/active recovery for the first two weeks, and 10 repetitions of 20-seconds work time followed by 100-seonds resting/active recovery for the rest of two weeks; targeted 90% HRmax) after 5-minute warm-up (10% HRmax). The supervisor (PI: Joon Young Kim and/or Graduate researcher: Wonhee Cho) will provide encouragement and supervision for exercise adherence. Heart rate (Polar, Polar Electro Oy, Kempele, Finland) and rating of perceived exertion (RPE; detail described in the questionnaire section) will be recorded.
  • Time-restricted eating — BEHAVIORAL
    Participants randomized into the TRE group will be instructed to consume all their calories within a 10-hour period. We will instruct participants that they can choose their time-window (early TRE \[7am - 5pm\] or late TRE \[1pm - 11pm\]), but it must remain constant for the duration of the study. Further, we will give no restrictions on the type of foods and/or the quantities individuals can consume. We will ask individuals to maintain their diet for the duration of the study. Participants will be given clear instructions on their diet and how to use the "MyFitnessPal" application. Participants will have their total daily energy requirement calculated using the following formula (Basal metabolic rate \[BMR\] x activity level) and will be told to eat that amount within their allotted time window. BMR will be calculated when participants have their body composition taken by the InBody. Participants will be told to start their 4-week diet the following day after visit.

Study Details

The primary aim of this randomized controlled trial is to examine the effects of a 4-week high-intensity interval training (HIIT) and time-restricted eating (TRE) intervention on cardiometabolic biomarkers in adolescents and young adults.

Key Dates

Start date
Mar 15, 2024
Status verified
Oct 2025
Primary completion
Sep 30, 2025
Completion
Dec 30, 2025

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: High-intensity interval training
    HIIT: The 4-week HIIT intervention will use a stationary bicycle performed 3 times/week (a total of 12 sessions over the 4-week), performing at the CRL. All participants will perform a 20-minute HIIT protocol (20 repetitions of 10-seconds work time followed by 50-seconds resting/active recovery for the first two weeks, and 10 repetitions of 20-seconds work time followed by 100-seonds resting/active recovery for the rest of two weeks; targeted 90% HRmax) after 5-minute warm-up (10% HRmax). The supervisor (PI: Joon Young Kim and/or Graduate researcher: Wonhee Cho) will provide encouragement and supervision for exercise adherence. Heart rate (Polar, Polar Electro Oy, Kempele, Finland) and rating of perceived exertion (RPE; detail described in the questionnaire section) will be recorded.
  • Experimental: Time-restricted eating
    Participants randomized into the TRE group will be instructed to consume all their calories within a 10-hour period. We will instruct participants that they can choose their time-window (early TRE \[7am - 5pm\] or late TRE \[1pm - 11pm\]), but it must remain constant for the duration of the study. Further, we will give no restrictions on the type of foods and/or the quantities individuals can consume. We will ask individuals to maintain their diet for the duration of the study. Participants will be given clear instructions on their diet and how to use the "MyFitnessPal" application. Participants will have their total daily energy requirement calculated using the following formula (Basal metabolic rate \[BMR\] x activity level) and will be told to eat that amount within their allotted time window. BMR will be calculated when participants have their body composition taken by the InBody. Participants will be told to start their 4-week diet the following day after visit.
  • No Intervention: Control Group
    Participants randomized into the control group will be told to maintain their daily lifestyle and dietary habits for the duration of the four weeks.

Primary Outcome Measure

Weight (kg) [ Time Frame: Baseline and after 4 weeks of intervention ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Syracuse UniversitySyracuseNew York13244
Joon Young Kim, PhD
[email protected]
315-443-2115
Joon Young Kim, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Syracuse, NY

By research site
Syracuse University· Syracuse, NY

Related Studies