Effects of Daily Beef Intake, as a Component of a Heart-Healthy Diet on Cellular Zinc

Part of paid clinical trials in Davis, California.

Sponsor
University of California, Davis
Study ID
NCT05236374
Status
Recruiting

Conditions

  • Inflammation
  • Metabolic Diseases
  • Vascular Diseases
  • Zinc Deficiency

Eligibility Criteria

Sex
ALL
Age
55 Years - 70 Years
Healthy Volunteers
Accepted

Interventions

  • Beef protein — OTHER
    Animal protein source

Study Details

The objective of the current study is to test the overarching hypothesis that the beef nutritive matrix is uniquely suited to direct dietary zinc to cellular compartments for improved metabolic function, leading to a greater effect on health outcomes. Specifically, whether beef, as a component of a healthy meal, will promote the absorption of zinc into cells, where the zinc will have greater effects on zinc-dependent metabolic processes supporting cardiovascular health. To maximize the observability of these beef-related effects, individuals who are 55- to 70-year-old who generally have a higher risk of zinc deficiency and cardiovascular disease will be enrolled.

Key Dates

Start date
Oct 1, 2022
Status verified
Feb 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION

Arms

  • Experimental: Beef Protein
    A beef stew, providing 8.8 mg zinc, 37.9 mg protein (approximately 500 kcal/d energy);
  • Active Comparator: Animal Protein
    A control plant protein stew, providing 8.8 mg zinc, 37.9 mg protein (approximately 500 kcal/d energy);

Primary Outcome Measure

microvascular function [ Time Frame: 4 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, Davis; Department of NutritionDavisCalifornia95616
Roberta Holt, PhD
530-752-4950

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