Criterion-learning Naming Treatment For Addressing Comprehension Deficits in Aphasia

Part of paid clinical trials in Elkins Park, Pennsylvania.

Sponsor
Albert Einstein Healthcare Network
Study ID
NCT07179458
Status
Enrolling By Invitation

Conditions

  • Aphasia

Eligibility Criteria

Sex
ALL
Age
18 Years - 89 Years
Healthy Volunteers
Not accepted

Interventions

  • Criterion-learning practice — BEHAVIORAL
    The experiments will be presented on a computer. On each criterion-learning trial, a picture is presented and the participant is asked to try to produce the name for the object with or without a cue. Correct-answer feedback is provided. Criterion learning involves presenting a block of items in fixed order, and on each trial, the experimenter or a voice-recognition component will code the response during the trial as correct/incorrect. When the item reaches its assigned criterion level, it is dropped from further training in a session.

Study Details

Aphasia is a disorder of spoken and written language, most commonly following a stroke. It is estimated that between 2.5 and 4 million Americans are living with aphasia today. A common problem in aphasia involves difficulty retrieving known words in the course of language production and comprehension. The overarching goal of this project is to develop and test early efficacy, efficiency, and the tolerability of a lexical treatment for aphasia in multiple-session regimens that are comprised of retrieval practice, distributed practice, and training dedicated to the elicitation of correct retrievals. The aim of this work is to add to and refine the evidence base for the implementation and optimization of these elements in the treatment of production and comprehension deficits in aphasia, and make important steps towards an ultimate goal of self-administered lexical treatment grounded in retrieval practice principles (RPP) to supplement traditional speech-language therapy that is appropriate for People with Aphasia (PWA) from a broad level of severity of lexical processing deficit in naming and/or comprehension. This project cumulatively builds on prior work to develop a theory of learning for lexical processing impairment in aphasia that aims to ultimately explain why and for whom familiar lexical treatments work, and how to maximize the benefits they confer.

Key Dates

Start date
Jun 24, 2024
Status verified
Sep 2025
Primary completion
Aug 31, 2028
Completion
Aug 31, 2028

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Criterion-learning practice
    This is a single-arm study

Primary Outcome Measure

Trained comprehension items [ Time Frame: approximately one-week and one-month following treatment ]

Locations (1)

FacilityCityStateZIPSite coordinators
Jefferson Moss Rehabilitation Research InstituteElkins ParkPennsylvania19027-

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Jefferson Moss Rehabilitation Research Institute· Elkins Park, PA

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