AI-Based Personalized Health and Self-Care

Part of paid clinical trials in Columbus, Ohio.

Sponsor
Emre Sezgin
Study ID
NCT07168382
Status
Recruiting
Apply to this trial

Conditions

  • Caregiver Burden
  • Health Status, Child and Infant Care
  • Preventative Care Services
  • Primary Health Care and Access to Primary Care
  • Social Needs Status
  • Technology Use to Support Caregivers
  • Unmet Health-Related Social Needs and Access to Community Resources

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • DAPHNE Chatbot Intervention — BEHAVIORAL
    The DAPHNE intervention consists of a conversational, AI-powered chatbot designed to identify and address health-related social needs (HRSNs) among caregivers of pediatric patients. Delivered via a secure mobile and web-based application, the chatbot facilitates natural language interactions to assess needs, generate personalized resource recommendations, and support real-time navigation to community-based services. Participants assigned to the intervention arm will have continuous access to the chatbot over a six-month period, including automated nudges, tailored prompts, and context-aware suggestions. The intervention is non-invasive and participant-driven.
  • Standard HRSN Screening and Referral (Usual Care) — OTHER
    Participants randomized to the control group will receive the standard-of-care HRSN screening and referral services as currently implemented in Nationwide Children's Hospital Primary Care Clinics. These services include in-clinic social needs assessments conducted during routine visits and referrals to internal or external resources, such as social work or care coordination teams. Participants in this group will not receive access to the DAPHNE chatbot.

Study Details

The goal of this clinical trial is to learn if the DAPHNE chatbot can improve caregiver engagement, usability, and integration of social care support tools into clinical workflows in caregivers of pediatric patients receiving care at the Nationwide Children's Hospital Primary Care Center (NCH PCC). This is a pilot randomized clinical trial. The main questions it aims to answer are: * Is the DAPHNE chatbot usable, acceptable, and minimally burdensome for caregivers over a 6-month period? * Can the DAPHNE chatbot be effectively integrated into primary care provider workflows? Researchers will compare the DAPHNE chatbot intervention arm to the standard of care control arm to see if the intervention improves caregiver-reported outcomes and provider workflow integration. Participants that are patients will be randomly assigned to either the DAPHNE chatbot group or the standard of care group. Complete surveys assessing usability, acceptability, and burden and participate in brief qualitative interviews to share feedback on their experience. Participants that are Primary Care providers will discuss integration of DAPHNE into clinical workflows and complete workflow integration assessments.

Key Dates

Start date
Apr 24, 2026
Status verified
May 2026
Primary completion
Aug 31, 2028
Completion
Aug 31, 2028

Study Design

Enrollment
70 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH

Arms

  • Experimental: Chatbot Access
    The intervention consists of a conversational, AI-powered chatbot designed to identify and address health-related social needs (HRSN) among caregivers of pediatric patients. Delivered via a secure mobile- and web-based application, the chatbot facilitates natural language interactions to assess needs, generate personalized resource recommendations, and support real-time navigation to community-based services. Participants assigned to the intervention arm will have continuous access to the chatbot over a 6-month period, including automated messages, tailored prompts, and context-aware suggestions. The intervention is non-invasive and participant driven.
  • Active Comparator: Standard of Care
    Participants randomized to the control group will receive the standard of care health-related social needs (HRSN) screening and referral services as currently implemented in Nationwide Children's Hospital primary care clinics. These services include in-clinic social needs assessments conducted during routine visits and referrals to internal or external resources, such as social work or care coordination teams. Participants in this group will not receive access to the DAPHNE chatbot. Study-related surveys and outcome assessments will be equivalent across both groups.
  • Experimental: Health Care Providers
    All health care providers will receive access to the chatbot.

Primary Outcome Measure

System Usability Scale (SUS) [ Time Frame: 1 month post-baseline and 3 months post-baseline for Caregivers. Providers will complete this at baseline only. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Nationwide Children's HospitalColumbusOhio43207
Emre Sezgin, PhD
[email protected]
(614) 722-3179
Emre Sezgin, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Columbus, OH

By research site
Nationwide Children's Hospital· Columbus, OH

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