Mechanisms of Visual Restoration After Occipital Stroke

Part of paid clinical trials in Rochester, New York.

Sponsor
University of Rochester
Study ID
NCT07134777
Status
Recruiting
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Conditions

  • Cortical Blindness
  • Hemianopia
  • Hemianopia Homonymous
  • Occipital Lobe Infarct
  • Stroke Ischemic
  • Vision Loss Partial
  • Visual Fields Hemianopsia

Eligibility Criteria

Sex
ALL
Age
21 Years - 80 Years
Healthy Volunteers
Accepted

Interventions

  • MRI — DIAGNOSTIC_TEST
    Functional MRI scan

Study Details

This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual visual system. Our goal is to improve understanding of the consequences of permanent visual cortex damage in humans, and to understand how visual training impacts the function of the residual visual system to restore perception.

Key Dates

Start date
Oct 17, 2025
Status verified
Nov 2025
Primary completion
Aug 1, 2029
Completion
Aug 1, 2029

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: Cortically Blind Subjects
    Subjects must exhibit unilateral stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 80 years.
  • Arm: Control Subjects
    Subjects with no history of neurological disorders and normal cognitive abilities.

Primary Outcome Measure

Identify visual areas of damage [ Time Frame: Baseline, Visit 2, Optional visits 3-7 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of RochesterRochesterNew York14642
Evan Burr, BA
[email protected]
585-275-5234
Krystel Huxlin, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
University of Rochester· Rochester, NY

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