Statistical Learning as a Novel Intervention for Cortical Blindness

Part of paid clinical trials in Rochester, New York.

Sponsor
University of Rochester
Study ID
NCT06578117
Status
Enrolling By Invitation

Conditions

  • Hemianopia, Homonymous
  • Hemianopsia
  • Occipital Lobe Infarct
  • Quadrantanopia
  • Stroke Hemorrhagic
  • Stroke, Ischemic
  • Vision Loss Partial
  • Visual Field Defect, Peripheral

Eligibility Criteria

Sex
ALL
Age
21 Years - 75 Years
Healthy Volunteers
Accepted

Interventions

  • Vision Training and Learning Task — DEVICE
    Participants will be seated at a computer, and will be shown a random-noise visual stimulus drifting in one of eight directions. Participants will be instructed to indicate the direction of motion they perceive using a Sony Access Controller or a computer keyboard. Sound cues during stimulus presentation will also be used to ensure participants are aware of stimulus onset during the training task. After several repetitions of this visual training, a second set of visual cues will be presented to evaluate participant's learning of the program. Responses will be provided in the same manner by input from the controller or the keyboard.

Study Details

This project aims to develop a novel visual training paradigm for use in visually-intact participants and those sufferings from stroke-induced visual impairments. Our task design is built upon theories of statistical learning to reduce the overall training burden while still producing profound improvements to visual abilities. Efficacy will be first established in visually-intact controls before testing in stroke survivors to assess the feasibility of this form of learning in the damaged visual system.

Key Dates

Start date
Nov 6, 2024
Status verified
Jan 2026
Primary completion
Oct 1, 2027
Completion
Oct 1, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Visual Training in Cortically Blind cohort
  • Experimental: Visual Training in Control cohort

Primary Outcome Measure

Explicit Learning - Response Time [ Time Frame: Baseline ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of Rochester Medical CenterRochesterNew York14642-

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By research site
University of Rochester Medical Center· Rochester, NY

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