Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

Part of paid clinical trials in Orange, California.

Sponsor
University of California, Irvine
Study ID
NCT07062172
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Low Dose CT Scan — DIAGNOSTIC_TEST
    Completed once after screening and eligibility is confirmed.

Study Details

This is a single-armed screening research study which screens immediate family member of lung cancer patients with a driver mutation to see if lung cancer can be inherited and whether researchers can find lung cancer early. Immediate family members of lung cancer patients will be 40-80 years old and screened using a low dose CT scan.

Key Dates

Start date
May 8, 2025
Status verified
Jul 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2028

Study Design

Enrollment
1,753 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING

Arms

  • Experimental: Low Dose CT Scan of First Degree Relatives of Lung Cancer Patients
    First degree relatives of patients with lung cancer with a known driver mutation will receive a low dose CT scan of the chest to screen for lung abnormality.

Primary Outcome Measure

Number of lung cancers found [ Time Frame: 2 years ]

Central Contacts

  • Chao Family Comprehensive Cancer Center University of California, Irvine
    1-877-827-8839
  • University of California Irvine Medical

Locations (1)

FacilityCityStateZIPSite coordinators
Chao Family Comprehensive Cancer Center University of California, IrvineOrangeCalifornia92868
Hari Keshava, MD
877-827-8839

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