Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Study ID
NCT07023887
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
FEMALE
Age
20 Years - 89 Years
Healthy Volunteers
Not accepted

Interventions

  • 6-12-25 Training Regimen — OTHER
    A conditioning regimen involving three exercises performed consecutively with minimal rest. Includes 4-6 repetitions at 4-0-1-0 tempo, 10-12 repetitions at 3-0-1-0 tempo, and 20-25 repetitions at 2-0-1-0 tempo.
  • 8x8 Training Regimen — OTHER
    A conditioning regimen optimizing high volume with short rest periods. Six exercises are performed consecutively with a 2-0-1-0 tempo and no rest between sets.
  • 5/5/5 Cluster Set Training Regimen — OTHER
    A hypertrophy regimen where an individual performs 5 repetitions at a tempo of 4 seconds during the eccentric movement of the exercise, while performing the concentric motion in 1 second then resting for 20 seconds and repeating the sequence two additional times to total three clusters of 5 repetitions.
  • Double Training Regimen — OTHER
    A hypertrophy regimen adding an additional set of lesser repetitions for a specified exercise at the end of a tri-set of exercises.

Study Details

This study investigates the impact of four standard of care, monitored group exercise regimens (resistance training) on conditioning and hypertrophy in women previously treated for breast cancer. The study will compare two conditioning regimens (6-12-25 and 8x8) and two hypertrophy regimens (5/5/5 cluster sets and double training) to assess changes in VO2 max, muscle mass, and fat mass.

Key Dates

Start date
May 21, 2025
Status verified
Feb 2026
Primary completion
Jul 15, 2026
Completion
Oct 15, 2026

Study Design

Enrollment
15 participants (estimated)

Primary Outcome Measure

Change in VO2 max [ Time Frame: Measured monthly during the 5-month exercise program at weeks 4, 8, 12, 16, and 20. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Allegheny General HospitalPittsburghPennsylvania15212
Clinical Trials Contact
[email protected]

Find similar trials in Pittsburgh, PA

By condition
Breast cancer
By specialty
OncologyBreast oncologyWomen's health
By research site
Allegheny General Hospital· Pittsburgh, PA

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