Imaging Studies in Corticobasal Syndrome

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Jennifer Whitwell
Study ID
NCT07000851
Status
Recruiting
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Conditions

  • Cortico Basal Degeneration
  • Corticobasal Degeneration
  • Corticobasal Degeneration (CBD)
  • Corticobasal Syndrome
  • Corticobasal Syndrome (CBS)
  • Corticobasal Syndrome(CBS)

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • C-11 ER176 Radiotracer — DIAGNOSTIC_TEST
    PET scan looking for inflammation
  • C-11 PiB — DIAGNOSTIC_TEST
    PET scan looking for amyloid protein
  • AV1451 Tau — DIAGNOSTIC_TEST
    Pet scan looking for Tau protein

Study Details

The primary goal of this study is to investigate inflammation and white matter damage in corticobasal syndrome and determine whether these processes are related to each other. The investigator's will address our goal by using neuroimaging and blood plasma biomarkers, as well as molecular pathology.

Key Dates

Start date
Jun 25, 2025
Status verified
Jul 2025
Primary completion
Mar 30, 2030
Completion
Mar 30, 2031

Study Design

Enrollment
80 participants (estimated)

Arms

  • Arm: Corticobasal Syndrome
    patients diagnosed with cbs
  • Arm: Healthy Control
    Healthy Control Volunteer

Primary Outcome Measure

The investigators will use C-11 ER176 PET imaging to evaluate neuroinflammation and white matter integrity in CBS [ Time Frame: approximately 4-5 years into study visits ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo ClinicRochesterMinnesota55905-

Find similar trials in Rochester, MN

By research site
Mayo Clinic· Rochester, MN

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