PET/MRI/EEG Imaging Study in Epilepsy

Part of paid clinical trials in Charlestown, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT06974305
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • FDG-PET/fMRI/EEG imaging — RADIATION
    Subject will undergo simultaneous EEG, fMRI, and FDG-PET imaging. This includes the use of a standard injected radioactive marker used in PET imaging.

Study Details

This study aims to better understand how epilepsy alters brain function through neuroimaging of healthy people and people with epilepsy. The study investigates how changes in brain metabolism (sugar consumption, measured by positron emission tomography \[FDG-PET\], and blood flow, measured by functional magnetic resonance imaging \[fMRI\]) relate to abnormal interictal electrical activity associated with epilepsy (measured by electroencephalography \[EEG\]). The study will also compare how the three imaging modalities localize regions of abnormal function in the brain.

Key Dates

Start date
Sep 21, 2023
Status verified
May 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
30 participants (estimated)

Arms

  • Arm: Healthy Controls
    Healthy control subjects with no major medical history
  • Arm: Subjects with Epilepsy
    Subjects diagnosed with epilepsy and with abnormal electrical activity recorded on interictal EEG.

Primary Outcome Measure

Image analysis [ Time Frame: Image analysis to be performed after imaging sessions are complete. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Athinoula A. Martinos CenterCharlestownMassachusetts02129
Ciprian Catana

Find similar trials in Charlestown, MA

By condition
Epilepsy
By specialty
NeurologyBrain disorders
By research site
Athinoula A. Martinos Center· Charlestown, MA

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