Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli

Part of paid clinical trials in Minneapolis, Minnesota.

Sponsor: University of Minnesota
Study ID: NCT06961864
Status: Recruiting

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Conditions

Healthy
Migraine
Visual Snow Syndrome

Eligibility Criteria

Sex: ALL
Age: 18 Years - 60 Years
Healthy Volunteers: Accepted

Interventions

Visual Adaptation — BEHAVIORAL
Presentation of visual stimuli to quantify the appearance of visual snow or its effects in the visual system of the brain.
Assessments and Questionnaires — BEHAVIORAL
Administration of clinical assessments and questionnaires to gather information about visual and mental symptoms, cognitive, and sensory function.
Functional Magnetic Resonance Imaging (fMRI) — DEVICE
7 tesla fMRI data will be acquired during visual paradigms designed to measure neural responses with and without adaptation.
Magnetic Resonance Imaging (MRS) — DEVICE
7 tesla MRS data will be acquired to quantify the concentrations of different brain chemicals in brain regions including visual cortex.

Study Details

The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: * Does VSS arise from spontaneous activity in brain pathways? * Where in the brain does the activity contributing to VSS arise? * How does brain activity contribute to VSS? Participants will: 1. Undergo assessments and questionnaires to understand visual and mental symptoms, cognitive, and sensory function. 2. Make visual judgements based on images presented to them both inside and outside a magnetic resonance imaging (MRI) machine. 3. Undergo scanning of their brain while inside of an MRI machine.