Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

Part of paid clinical trials in Boca Raton, Florida.

Sponsor
Center for International Blood and Marrow Transplant Research
Study ID
NCT00785525
Phase
PHASE3
Status
Recruiting
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Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

  • Filgrastim — DRUG
    PBSC donors will receive 10 µg/kg of filgrastim subcutaneously each day of a five day mobilization schedule.

Study Details

The purpose of the study is to: * Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors * Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis * Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated donor hematopoietic stem cell transplant recipients * Determine the acceptability of stem cell donation by filgrastim stimulated apheresis in normal donors

Key Dates

Start date
Feb 28, 1997
Status verified
Jan 2025
Primary completion
Jan 31, 2030
Completion
Jan 31, 2030

Study Design

Enrollment
60,000 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Primary Outcome Measure

Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from NMDP donors. [ Time Frame: Ongoing ]

Central Contacts

Locations (4)

FacilityCityStateZIPSite coordinators
Gift of Life Bone Marrow FoundationBoca RatonFlorida33431-
C.W. Bill Young Marrow Donor CenterRockvilleMaryland20852
Michael Donnelly, MD (PRINCIPAL_INVESTIGATOR)
Be The MatchMinneapolisMinnesota55401-
DKMS AmericasNew YorkNew York10016-

Find similar trials in Boca Raton, FL

By research site
Gift of Life Bone Marrow Foundation· Boca Raton, FLC.W. Bill Young Marrow Donor Center· Rockville, MDBe The Match· Minneapolis, MNDKMS Americas· New York, NY

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