Effect of Tirzepatide on Markers of MASLD in Patients With Obesity

Part of paid clinical trials in Albuquerque, New Mexico.

Sponsor
University of New Mexico
Study ID
NCT06934642
Phase
EARLY_PHASE1
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Tirzepatide — DRUG
    The drug is being studied to better understand the biological effects of tirzepatide on MASLD.

Study Details

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is the most common cause of chronic liver disease worldwide and predominately affects individuals with overweight and obesity, as well as those with type 2 diabetes and cardiovascular disease. Tirzepatide is a medication used to treat type 2 diabetes and obesity. It has also been shown to help with MASLD. The purpose of this study is to study how tirzepatide affects the liver in patients with MASLD. Participants will be asked to: * Take tirzepatide for 12 months. * Come in for clinic visits every 3 months. * Have blood drawn at baseline, 6, and 12 months. * Complete a liver ultrasound at baseline and at 12 months.

Key Dates

Start date
Jun 30, 2025
Status verified
Jul 2025
Primary completion
Aug 31, 2026
Completion
Aug 31, 2026

Study Design

Enrollment
8 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Intervention Arm
    Individuals in the intervention arm (only arm) will receive tirzepatide for 12 months.

Primary Outcome Measure

Biomarkers associated with MASLD [ Time Frame: 12 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of New Mexico Health Sciences CenterAlbuquerqueNew Mexico87131
Kristen Gonzales, MD
[email protected]
505-272-3840
Kristen Gonzales, MD (PRINCIPAL_INVESTIGATOR)
Eliseo Castillo, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Albuquerque, NM

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
University of New Mexico Health Sciences Center· Albuquerque, NM

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