A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Eli Lilly and Company
Study ID
NCT07282600
Phase
PHASE3
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Eloralintide — DRUG
    Administered SC
  • Placebo — DRUG
    Administered SC

Study Details

The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo for body weight reduction in participants with overweight or obesity and type 2 diabetes. Participation in the study will last about 75 weeks.

Key Dates

Start date
Dec 15, 2025
Status verified
Jun 2026
Primary completion
Jan 31, 2028
Completion
Feb 29, 2028

Study Design

Enrollment
1,035 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Eloralintide Dose 1
    Participants will receive eloralintide subcutaneously (SC)
  • Experimental: Eloralintide Dose 2
    Participants will receive eloralintide SC
  • Experimental: Eloralintide Dose 3
    Participants will receive eloralintide SC
  • Experimental: Eloralintide Dose 4
    Participants will receive eloralintide SC
  • Placebo Comparator: Placebo
    Participants will receive placebo SC

Primary Outcome Measure

Percent Change from Baseline in Body Weight [ Time Frame: Baseline, Week 64 ]

Central Contacts

  • Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
    317-615-4559
    [email protected]
  • Physicians interested in becoming principal investigators please contact
    [email protected]

Locations (60)

FacilityCityStateZIPSite coordinators
Birmingham Clinical ResearchBirminghamAlabama35209
205-870-4343
Nova Law (PRINCIPAL_INVESTIGATOR)
Cullman Clinical TrialsCullmanAlabama35055
256-708-2826
Randall Quinn (PRINCIPAL_INVESTIGATOR)
Tucson Clinical Research InstituteTucsonArizona85712
Girish Karamchandani (PRINCIPAL_INVESTIGATOR)
San Fernando Valley Health InstituteCanoga ParkCalifornia91304
818-222-6868
Jeffrey London (PRINCIPAL_INVESTIGATOR)
AMCR InstituteEscondidoCalifornia92025
760-466-1520
Jenine Stone (PRINCIPAL_INVESTIGATOR)
NorCal Medical Research, IncGreenbraeCalifornia94904
415-461-1585
Linda Gaudiani (PRINCIPAL_INVESTIGATOR)
Inglewood ClinicalInglewoodCalifornia90301
310-693-5000
Maricor Grio (PRINCIPAL_INVESTIGATOR)
Ark Clinical ResearchLong BeachCalifornia90815
Martha Navarro (PRINCIPAL_INVESTIGATOR)
Pacific Clinical StudiesLos AlamitosCalifornia90720
562-598-0600 ext 205
Etsegenet Ayele (PRINCIPAL_INVESTIGATOR)
Care Access - Santa ClaritaSanta ClaritaCalifornia91321
661-371-7272
Sina Tebi (PRINCIPAL_INVESTIGATOR)
Encompass Clinical ResearchSpring ValleyCalifornia91978
619-660-9068
Hanid Audish (PRINCIPAL_INVESTIGATOR)
Diablo Clinical Research, Inc.Walnut CreekCalifornia94598
925-930-7267
Bonnie Kimmel (PRINCIPAL_INVESTIGATOR)
Care Access - AuroraAuroraColorado80012
720-368-4865
Mauricio Waintrub (PRINCIPAL_INVESTIGATOR)
New England Research Associates, LLCBridgeportConnecticut06606
203-374-9816
Ilja Hulinsky (PRINCIPAL_INVESTIGATOR)
CMR of Greater New Haven, LLCHamdenConnecticut06517
Jillian Reid (PRINCIPAL_INVESTIGATOR)
Arrow Clinical TrialsDaytona BeachFlorida32117
386-278-8000
David Billmeier (PRINCIPAL_INVESTIGATOR)
Care Access - Delray BeachDelray BeachFlorida33484
401-773-7855
Sudhir Bansal (PRINCIPAL_INVESTIGATOR)
Fleming Island Center for Clinical ResearchFleming IslandFlorida32003
904-621-0390
Jennifer Sidey (PRINCIPAL_INVESTIGATOR)
Nature Coast Clinical Research - InvernessInvernessFlorida34452
352-341-2100
Paul Hellstern (PRINCIPAL_INVESTIGATOR)
Jacksonville Center for Clinical ResearchJacksonvilleFlorida32216
904-730-0101
Jeffry Jacqmein (PRINCIPAL_INVESTIGATOR)
Flourish Research Acquisition, LLC dba Flourish Research - North MiamiMiamiFlorida33138
786-772-0411
Rimsky Denis (PRINCIPAL_INVESTIGATOR)
New Horizon Research CenterMiamiFlorida33165
305-226-3933
Lazaro Nunez (PRINCIPAL_INVESTIGATOR)
Adult Medicine of Lake County, Inc.Mt. DoraFlorida32757
352-383-8222
Shirley Nagel (PRINCIPAL_INVESTIGATOR)
American Research Centers of FloridaPembroke PinesFlorida33027
954-237-3799
Luis del Prado Rodriguez (PRINCIPAL_INVESTIGATOR)
Clinical Site Partners, LLC dba Flourish ResearchWinter ParkFlorida32789
407-740-8078
Monica Aggarwal (PRINCIPAL_INVESTIGATOR)
Teak Research Consults - DunwoodyDunwoodyGeorgia30338
Shani Belgrave (PRINCIPAL_INVESTIGATOR)
Teak Research ConsultsLawrencevilleGeorgia30043
Kamar Alabi (PRINCIPAL_INVESTIGATOR)
The Jones Center Clinical ResearchMaconGeorgia31210
Susan Garcia Castillo (PRINCIPAL_INVESTIGATOR)
Pacific Diabetes & Endocrine CenterHonoluluHawaii96817
808-526-0303
ALAN PARSA (PRINCIPAL_INVESTIGATOR)
NorthShore University Health SystemSkokieIllinois60077
847-663-8540
Liana Billings (PRINCIPAL_INVESTIGATOR)
DM Clinical Research - IndianapolisIndianapolisIndiana46254
463-271-3050
Brandon Essink (PRINCIPAL_INVESTIGATOR)
Clinical Trials Management, LLC d/b/a Flourish ResearchMetairieLouisiana70006
504-455-1310
David Dulitz (PRINCIPAL_INVESTIGATOR)
IMA Clinical Research Monroe - ArmandMonroeLouisiana71201
Clinton Guillory (PRINCIPAL_INVESTIGATOR)
Centennial Medical GroupColumbiaMaryland21045
410-730-3399
Rajiv Dua (PRINCIPAL_INVESTIGATOR)
Lucida Clinical TrialsNew BedfordMassachusetts02740
508-720-2015
David Shih (PRINCIPAL_INVESTIGATOR)
Clinical Research ProfessionalsChesterfieldMissouri63005
636-220-1200
Timothy Jennings (PRINCIPAL_INVESTIGATOR)
Clinvest Headlands LlcSpringfieldMissouri65807
417-883-7889
Cory Bethmann (PRINCIPAL_INVESTIGATOR)
Hypertension & Nephrology AssociationEatontownNew Jersey07724
Kenneth Liss (PRINCIPAL_INVESTIGATOR)
IMA Clinical Research WarrenWarren TownshipNew Jersey07059
Nancy Phillips (PRINCIPAL_INVESTIGATOR)
Albuquerque Clinical Trials, Inc.AlbuquerqueNew Mexico87102
505-224-7407
Satkirin Khalsa (PRINCIPAL_INVESTIGATOR)
NYC Research INCLong Island CityNew York11106
516-574-9232
Anastasios Manessis (PRINCIPAL_INVESTIGATOR)
PharmQuest Life Sciences, LLCGreensboroNorth Carolina27408
336-574-8020
Alexander Murray (PRINCIPAL_INVESTIGATOR)
West Clinical ResearchMorehead CityNorth Carolina28557
252-515-0050
Patrick Morgante (PRINCIPAL_INVESTIGATOR)
Trial Management Associates - Wilmington - Floral ParkwayWilmingtonNorth Carolina28403
William Jones (PRINCIPAL_INVESTIGATOR)
Lillestol ResearchFargoNorth Dakota58104
701-232-7705
Michael Lillestol (PRINCIPAL_INVESTIGATOR)
Care Access - LimaLimaOhio45805
Jimmy Alele (PRINCIPAL_INVESTIGATOR)
Summit HeadlandsPortlandOregon97210
Andre Barkhuizen (PRINCIPAL_INVESTIGATOR)
Preferred Primary Care Physicians, Preferred Clinical Research-St. ClairPittsburghPennsylvania15243
412-942-0023
Daniel Austin (PRINCIPAL_INVESTIGATOR)
Preferred Primary Care PhysiciansUniontownPennsylvania15401
724-438-1479
Richard Cook II (PRINCIPAL_INVESTIGATOR)
Accellacare - Mt PleasantMt. PleasantSouth Carolina29464
843-849-1880
Richard Mills (PRINCIPAL_INVESTIGATOR)
IMA Clinical Research AustinAustinTexas78745
Yu-Mei Liu (PRINCIPAL_INVESTIGATOR)
Private Practice - Dr. Osvaldo A. BruscoCorpus ChristiTexas78414
361-885-0448
Osvaldo Brusco (PRINCIPAL_INVESTIGATOR)
Velocity Clinical Research, DallasDallasTexas75230
Dan Lender (PRINCIPAL_INVESTIGATOR)
Diabetes and Thyroid Center of Ft. WorthFort WorthTexas76132
817-263-0007
Anjanette Tan (PRINCIPAL_INVESTIGATOR)
Juno ResearchHoustonTexas77040
713-779-5494
Damaris Vega (PRINCIPAL_INVESTIGATOR)
Southern Endocrinology AssociatesMesquiteTexas75149
214-693-0904
Sumana Gangi (PRINCIPAL_INVESTIGATOR)
Research Your HealthPlanoTexas75093
9729991155 x103
Michele Reynolds (PRINCIPAL_INVESTIGATOR)
IMA Clinical Research San AntonioSan AntonioTexas78229
210-692-7157
Priscilla Thomas (PRINCIPAL_INVESTIGATOR)
Ogden Clinic - Canyon ViewOgdenUtah84404
385-271-0684
Stephen Bruce (PRINCIPAL_INVESTIGATOR)
Diabetes & Endocrine Treatment SpecialistsSandy CityUtah84093
801-816-1010
Timothy Graham (PRINCIPAL_INVESTIGATOR)

Find similar trials in Birmingham, AL

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Obesity / overweight
By specialty
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By research site
Birmingham Clinical Research· Birmingham, ALCullman Clinical Trials· Cullman, ALTucson Clinical Research Institute· Tucson, AZSan Fernando Valley Health Institute· Canoga Park, CAAMCR Institute· Escondido, CANorCal Medical Research, Inc· Greenbrae, CA

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