Affect-based Impulsivity in Borderline Personality Disorder

Part of paid clinical trials in Chapel Hill, North Carolina.

Sponsor
University of North Carolina, Chapel Hill
Study ID
NCT06880640
Status
Recruiting
Apply to this trial

Conditions

  • Borderline Personality Disorder (BPD)
  • Healthy Controls Group - Age and Sex-matched

Eligibility Criteria

Sex
ALL
Age
18 Years - 45 Years
Healthy Volunteers
Accepted

Interventions

  • Stress Induction — BEHAVIORAL
    Participants will complete the Trier Social Stress Test to induce stress, which includes a public speaking simulation and mental arithmetic.

Study Details

The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old. The main question it aims to answer is how neuroendocrine activity impacts decision-making. Participants will complete online behavioral tasks, a stress induction procedure, self-report surveys, and a cognitive assessment. During the session, psychophysiological measures will be collected, including electrocardiogram (ECG) and cardiac impedance (ICG) to monitor heart rate and blood flow, as well as electrodermal activity (EDA), blood drop samples, and saliva collection to assess nervous system activity.

Key Dates

Start date
Sep 21, 2025
Status verified
Sep 2025
Primary completion
Aug 31, 2026
Completion
Aug 31, 2026

Study Design

Enrollment
106 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Stress
    Participants will undergo a controlled stress induction approximately 1 hour and 35 minutes into Session 1.

Primary Outcome Measure

Goal-directed decision-making in the Social Decision Tree Task (SDTT) [ Time Frame: Collected for 40 minutes ~2 hours into one-time study visit ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of North Carolina at Chapel HillChapel HillNorth Carolina27514
Michael N Hallquist, PhD
[email protected]
412-613-9306

Find similar trials in Chapel Hill, NC

By research site
University of North Carolina at Chapel Hill· Chapel Hill, NC

Related Studies