Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise

Part of paid clinical trials in Cambridge, Massachusetts.

Sponsor
Spaulding Rehabilitation Hospital
Study ID
NCT06826781
Status
Recruiting
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Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
18 Years - 30 Years
Healthy Volunteers
Accepted

Interventions

  • Q30 Q-Collar — DEVICE
    Participants will complete a series of tests (sit-to-stand, resistive breathing, and graded bike test) while wearing a Q-Collar.
  • Not wearing Q-Collar — OTHER
    Participants will undergo the same study procedures without wearing the Q-Collar.

Study Details

The goal of this clinical trial is to learn how the FDA-cleared Q-Collar device affects brain blood flow regulation during rest and exercise in healthy adults. The main questions this study aims to answer are: 1. How does the Q-Collar affect brain blood flow when there are quick changes in blood pressure, like when standing up quickly, or when breathing against resistance? 2. How does the Q-Collar affect brain blood flow during exercise? Researchers will compare sessions where participants wear the Q-Collar to sessions where they do not wear the device to see if the Q-Collar improves brain blood flow during both rest and exercise. Participants will: * Complete two study visits, each 1 to 4 weeks apart. * Perform a series of tasks, including standing tests, breathing tests, and exercise on a stationary bike, while their heart rate, brain blood flow, and other body functions are monitored. * Wear the Q-Collar during one of the sessions and not wear it during the other session. The order of the sessions will be randomly assigned.

Key Dates

Start date
Jul 23, 2025
Status verified
Oct 2025
Primary completion
Jul 23, 2026
Completion
Aug 23, 2026

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Cerebrovascular Control with Q-Collar
    Participants will undergo measurements of cerebral blood flow during changes in body position (sit-to-stand) and resistance breathing tasks while wearing a properly fitted Q-collar to evaluate how the Q-Collar affects cerebrovascular responses to rapid and sinusoidal shifts in blood pressure.
  • Placebo Comparator: Cerebrovascular Control without Q-Collar
    Participants will undergo measurements of cerebral blood flow during changes in body position (sit-to-stand) and resistance breathing tasks without wearing a Q-collar.

Primary Outcome Measure

Sit-to-Stand Test: Autoregulatory Slope [ Time Frame: 2 study visits within a 4 week time frame ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Spaulding Rehabilitation HospitalCambridgeMassachusetts02138
Glen Picard, MS
[email protected]
617-758-5511

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By research site
Spaulding Rehabilitation Hospital· Cambridge, MA

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