Mapping Auricular Vagus Nerve Circuitry

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT00200889
Phase
EARLY_PHASE1
Status
Recruiting
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Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • active TEAS — DEVICE
    non-painful active transcutaneous electro-acupoint stimulation will be delivered to the abdomen and leg

Study Details

This study will determine how noninvasive nerve stimulation affects human brain, stomach, and autonomic activity.

Key Dates

Start date
Aug 22, 2023
Status verified
Oct 2025
Primary completion
Jun 30, 2028
Completion
Jun 30, 2028

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Congruent
    Participants receive briefings on expectations of stimulation effects on gastric motility consistent with the literature.
  • Experimental: Incongruent
    Participants receive briefings on expectations of stimulation effects on gastric motility inconsistent with the literature.

Primary Outcome Measure

Brain activity during functional magnetic resonance imaging (fMRI) [ Time Frame: 1 hour ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Massachusetts General HospitalBostonMassachusetts02114
Andy Bolender
[email protected]
Vitaly Napadow, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
Massachusetts General Hospital· Boston, MA

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