Food Orders on Blood Glucose and Fuel Use At Rest

Part of paid clinical trials in Norfolk, Virginia.

Sponsor
Old Dominion University
Study ID
NCT06763562
Status
Recruiting
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Conditions

  • Fat Burn
  • Glucose Metabolism Disorders
  • Hunger

Eligibility Criteria

Sex
ALL
Age
18 Years - 70 Years
Healthy Volunteers
Accepted

Interventions

  • Carbohydrate-first meal — OTHER
    Rice eaten first (150 grams), followed by edamame (150 grams) and butter (10 grams)
  • Carbohydrate-last meal — OTHER
    Edamame (150 grams) and butter (10 grams) eaten first, followed by rice (150 grams)

Study Details

Consuming a carbohydrate-rich food as the final food in a meal, as compared to the first food in a meal, has been shown to reduce blood glucose levels after eating in both diabetes patients and in healthy controls. However, gaps remain in the literature in this area of research, and currently little is known about how substrate (fuel) use is impacted by altering food order. In addition, most studies to date have used a mix of meat and plant foods, while little research has focused exclusively on vegetarian foods. This randomized experiment will examine how altering the order of foods eaten in a vegetarian meal impacts blood glucose and fuel utilization at rest.

Key Dates

Start date
Jan 5, 2025
Status verified
Jan 2025
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Carbohydrate-first meal
  • Experimental: Carbohydrate-last meal

Primary Outcome Measure

Respiratory exchange ratio [ Time Frame: 90 minutes (baseline/premeal and at 30, 60, and 90 minutes postmeal) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Old Dominion University Human Performance LaboratoryNorfolkVirginia23529
Patrick Wilson, PhD
[email protected]

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Old Dominion University Human Performance Laboratory· Norfolk, VA

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