Animal and Plant Proteins and Glucose Metabolism

Part of paid clinical trials in Columbia, Missouri.

Sponsor
University of Missouri-Columbia
Study ID
NCT03994367
Status
Recruiting
Apply to this trial

Conditions

  • Glucose Metabolism Disorders
  • Metabolic Syndrome
  • Metabolic Syndrome, Protection Against

Eligibility Criteria

Sex
ALL
Age
21 Years - 70 Years
Healthy Volunteers
Accepted

Interventions

  • High animal protein isolate — OTHER
    Increased dietary protein content from animal protein isolates
  • High animal protein whole food — OTHER
    Increased dietary protein content from animal protein whole food
  • High plant protein isolate — OTHER
    Increased dietary protein content from plant protein isolates
  • High plant protein whole food — OTHER
    Increased dietary protein content from animal protein whole food

Study Details

The goal of this proposal is to determine the effect of a high protein diet in which the increase in protein intake is derived from different sources (animal vs plant and protein-rich whole foods vs protein isolates) on: i) liver and muscle insulin sensitivity; ii) the metabolic response to a meal, and iii) 24-h plasma concentration profiles of glucose, glucoregulatory hormones, and protein-derived metabolites purported to cause metabolic dysfunction.

Key Dates

Start date
Jul 12, 2019
Status verified
Apr 2026
Primary completion
Feb 25, 2028
Completion
Apr 25, 2028

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • No Intervention: Standard protein (control)
  • Experimental: High animal protein isolate
  • Experimental: High animal protein whole food
  • Experimental: High plant protein isolate
  • Experimental: High plant protein whole food

Primary Outcome Measure

24-hour plasma glucose concentration [ Time Frame: up to 12 weeks after the intervention ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Missouri School of MedicineColumbiaMissouri65212
BETTINA MITTENDORFER
[email protected]
618-610-3465
[email protected]

Find similar trials in Columbia, MO

By research site
University of Missouri School of Medicine· Columbia, MO

Related Studies