Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT06633224
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Blood Specimen Collection — PROCEDURE
    Blood samples will be obtained throughout the course of the study
  • Stool Specimen Collection — OTHER
    Stool samples will be obtained throughout the course of the study
  • Quality of Life (QOL) Questionnaires — OTHER
    Surveys will be given throughout the course of the study.

Study Details

Cancer-related fatigue (CRF) is a significant problem for cancer patients. This prospective, basic science, observational study will evaluate for changes in CRF associated with molecular characteristics prior to, during, and at the completion of non-investigational, standard-of-care, combined chemotherapy and radiation therapy (CCRT) and to develop and assess predictive models for CRF severity.

Key Dates

Start date
Dec 27, 2024
Status verified
Sep 2025
Primary completion
Sep 1, 2026
Completion
Sep 1, 2027

Study Design

Enrollment
125 participants (estimated)

Arms

  • Arm: Cancer Patients
    Participants will have blood and stool samples collected within 5 days of any pre or post treatment timepoint prior to, during, at completion of therapy and up to 34 weeks following non-investigational, standard of care, CCRT. Participants will also be given quality of life questionnaires to complete throughout the course of the study.

Primary Outcome Measure

Measure associations between changes in cancer-related fatigue (CRF) and changes in gene expression over time [ Time Frame: Up to 34 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, San FranciscoSan FranciscoCalifornia94143
Jamese Johnson
[email protected]
415-530-9805
[email protected]
877-827-3222
Sue Yom, MD (PRINCIPAL_INVESTIGATOR)
Kord M Kober, PhD (PRINCIPAL_INVESTIGATOR)

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