Mechanisms for Laser-Induced Rejuvenation

Part of paid clinical trials in Fairborn, Ohio.

Sponsor
Wright State University
Study ID
NCT06489301
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Fractionated Laser Resurfacing — DEVICE
    A rejuvenating laser that makes tiny holes in the very superficial part of the skin.

Study Details

It has shown that laser wounding of geriatric skin protects it against skin cancer. The purpose of this study is to determine the origin of cells called fibroblasts which are present after treatment with Fractionated Laser Resurfacing (FLR). These cells restore a youth-like ultraviolet B (UVB) response, but where they come from is currently unknown. The study recruits subjects who are scheduled to undergo abdominoplasties to investigate the origin of those cells stimulated by laser treatment.

Key Dates

Start date
Jul 16, 2025
Status verified
May 2026
Primary completion
Dec 31, 2028
Completion
Dec 31, 2028

Study Design

Enrollment
12 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION

Arms

  • Experimental: Fractionated Laser Resurfacing
    At 14 days prior to scheduled surgery a 5x5cm square on the left abdomen within the region of skin to be excised and treated with fractionated laser resurfacing. Then at 7 days prior to scheduled surgery a 5 cm diameter circle on the right abdomen within the region of skin to be excised, at least 10 cm away from the square, is treated with fractionated laser resurfacing.

Primary Outcome Measure

To test if the new fibroblasts that develop in response to fractionated laser resurfacing (FLR) wounding are derived from blood-derived monocytes. [ Time Frame: 2 weeks prior to skin removal and 1 week prior to skin removal ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Pharmacology Translational UnitFairbornOhio45324
Pharmacology Translational Unit
[email protected]
937-245-7500

Find similar trials in Fairborn, OH

By condition
Skin cancer
By specialty
OncologySkin cancerDermatology
By research site
Pharmacology Translational Unit· Fairborn, OH

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