Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application

Part of paid clinical trials in Worcester, Massachusetts.

Sponsor
Dartmouth-Hitchcock Medical Center
Study ID
NCT06425029
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Experimental Intervention (Music A) — OTHER
    Participants will be asked to listen to Music A on their personal device daily, at a time most convenient for them.
  • Active Comparator Intervention (Music B) — OTHER
    Participants will be asked to listen to music B on their personal device daily, at a time most convenient for them.
  • Active Comparator Intervention (Music C) — OTHER
    Participants will be asked to listen to music C on their personal device daily, at a time most convenient for them.

Study Details

This is a prospective, placebo-controlled, double-blinded randomized study of self-administered auditory intervention in a naturalistic home environment.

Key Dates

Start date
Jul 22, 2025
Status verified
May 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2027

Study Design

Enrollment
24 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Music Piece A
    Participants will be asked to listen to a musical excerpt previously shown to have a positive effect on epileptic activity in human brain.
  • Active Comparator: Music Piece B
    Participants will be asked to listen to a musical except very similar to the experimental stimuli that has not been shown to have a positive effect on epileptic activity.
  • Active Comparator: Music Piece C
    Participants will select a preferred excerpt from several popular musical genres. This piece is modified to have some similarities to the experimental musical excerpt.

Primary Outcome Measure

Music Intervention and its effects on epileptic activity in human brain [ Time Frame: Baseline, Week 3-4, Week 9-10, and Weeks 13-14, (Approximately 4 1/2 Months) ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
University of Massachusetts Chan Medical SchoolWorcesterMassachusetts01655
Natalie Erlich-Malona, MD
[email protected]
Felicia Chu, MD (SUB_INVESTIGATOR)
Natalie Erlich-Malona, MD (PRINCIPAL_INVESTIGATOR)
Dartmouth-Hitchcock Medical CenterLebanonNew Hampshire03756
Anastasia Kanishcheva, MPH
[email protected]
603-650-0260
Brian C Fidali, MD
[email protected]
603-650-5104
Brian C Fidali, MD (PRINCIPAL_INVESTIGATOR)
Barbara C Jobst, MD (SUB_INVESTIGATOR)

Find similar trials in Worcester, MA

By condition
Epilepsy
By specialty
NeurologyBrain disorders
By research site
University of Massachusetts Chan Medical School· Worcester, MADartmouth-Hitchcock Medical Center· Lebanon, NH

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