Regenerative Treatment of Peri-implantitis

Part of paid clinical trials in Ann Arbor, Michigan.

Sponsor
University of Michigan
Study ID
NCT06153212
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Membrane placement with bone grafting — PROCEDURE
    The diseased dental implant will be cleaned and the bone defect will be filled with bone graft and covered by a membrane.

Study Details

The purpose of this study is to study the use of a new type of d-PTFE membrane called reinforced PTFE Mesh (RPM) with dental surgery. The regenerative outcomes of RPM membranes and collagen membrane for surgical reconstructive treatment of peri-implantitis (gum disease around implants) will be compared.

Key Dates

Start date
Nov 2, 2023
Status verified
Jan 2026
Primary completion
Jun 1, 2026
Completion
Dec 1, 2026

Study Design

Enrollment
32 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: PTFE Mesh Membrane
    A reinforced PTFE Mesh membrane will be used to cover the bone graft.
  • Active Comparator: Collagen membrane
    A collagen membrane will be used to cover the bone graft.

Primary Outcome Measure

Probing depth measurements in millimeters [ Time Frame: About 5 weeks before baseline surgery and at 8.5 months after baseline surgery. ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of Michigan School of DentistryAnn ArborMichigan48109-

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By research site
University of Michigan School of Dentistry· Ann Arbor, MI

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