Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT06063876
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Accepted

Interventions

  • Induction of experimental peri-implant mucositis — PROCEDURE
    Patients will refrain from oral hygiene measures at the implant sites for 3 weeks to induce peri-implant mucositis, by using a stent in the included implant during oral hygiene.
  • Resolution of experimental peri-implant mucositis — PROCEDURE
    Patients will reinstitute oral hygiene measures, receive an oral prophylaxis and oral hygiene instructions and will be evaluated during 3 weeks.

Study Details

This controlled clinical trial will assess clinically, immunologically, and microbiologically the healing of experimental peri-implant mucositis (PIM) lesions in implants treated previously with implantoplasty (IP) compared to those treated without IP.

Key Dates

Start date
Sep 5, 2023
Status verified
Oct 2025
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION

Arms

  • Experimental: Implants with history of peri-implantitis
    Implant(s) treated previously for peri-implantitis with or without exposed polished surface, no PD \> 4 mm and \< 50% bone loss.

Primary Outcome Measure

Changes in the modified Gingival Index (mGI) between 21 and 42 days [ Time Frame: At 21 and 42 days ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of Pittsburgh School of Dental MedicinePittsburghPennsylvania15213-

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University of Pittsburgh School of Dental Medicine· Pittsburgh, PA

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