Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Brigham and Women's Hospital
Study ID
NCT06099093
Phase
PHASE4
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
MALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • 18F-DCFPyl — DRUG
    Fluorine-labeled small molecule, via intravenous infusion per protocol.

Study Details

The purpose of this research study is to see how well an imaging test, called 18FDCFPyL prostate specific membrane antigen (PSMA) positron emission tomography (PET), can show the extent of prostate cancer when comparing to 68Ga-PSMA-11 PET/CT (another type of diagnostic scan for prostate cancer).

Key Dates

Start date
Apr 1, 2024
Status verified
Nov 2025
Primary completion
Dec 1, 2026
Completion
Dec 1, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: 18F-DCFPYL-PSMA PET
    Study procedures will be conducted as follows: * Baseline screening visit with PSMA-PET/CT scan with Ga-PSMA-11. * In-clinic visit with exam and PSMA-PET/CT scan with 18F-DCFPyl per standard institutional procedures. * Standard of care therapy. * Follow up every 3 months via chart review for 12 months, with the purpose of seeing how participants respond to 177Luvipivotide tetraxetan treatment.

Primary Outcome Measure

Proportion of Participants with PSMA-Positive Lesion [ Time Frame: 1 Day ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Brigham and Womens HospitalBostonMassachusetts02215
Heather A Jacene, MD
[email protected]
617 632-3767
Heather A Jacene, MD (PRINCIPAL_INVESTIGATOR)
Dana Farber Cancer InstituteBostonMassachusetts02115
Heather Jacene, MD
[email protected]
617-632-3767
Heather Jacene, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Boston, MA

By condition
Prostate cancer
By specialty
OncologyProstate oncologyMen's healthUrology
By research site
Brigham and Womens Hospital· Boston, MADana Farber Cancer Institute· Boston, MA

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