Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT01961713
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
MALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

This study will evaluate a method to detect tumor cells that are circulating in the blood without getting a biopsy. The investigators already know from other studies that cancer tumors shed a small number of cells into the bloodstream every day. These are called circulating tumor cells (CTCs). Some early studies indicate the amount and type of CTCs in the blood can help determine the status of the tumor itself and the way it is responding to treatment. In this study, the investigators will compare the number of CTCs in the blood at different time frames before and after surgery to remove the prostate.

Key Dates

Start date
Apr 30, 2010
Status verified
Nov 2025
Primary completion
Dec 31, 2025
Completion
Dec 31, 2025

Study Design

Enrollment
200 participants (estimated)

Arms

  • Arm: Prostatectomy
    Subjects with prostate cancer diagnosed on prostate biopsy who undergo radical prostatectomy at Massachusetts General Hospital

Primary Outcome Measure

Relationship between CTC quantity and pathologic stage [ Time Frame: Up to 2 weeks after prostatectomy ]

Central Contacts

  • Richard J Lee, MD, PhD
    617-724-4000

Locations (1)

FacilityCityStateZIPSite coordinators
Massachsuetts General HospitalBostonMassachusetts02114-

Find similar trials in Boston, MA

By condition
Prostate cancer
By specialty
OncologyProstate oncologyMen's healthUrology
By research site
Massachsuetts General Hospital· Boston, MA

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