OCT Vibrography for Biomechanical Properties of Tissues

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT05759780
Status
Recruiting
Apply to this trial

Conditions

  • Cornea
  • Gingival Diseases
  • Skin Diseases

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Accepted

Interventions

  • Optical imaging of the tissues — DEVICE
    OCT vibrography

Study Details

The overall goal of this study is to develop OCT Vibrography (aka OCT elastography) as a novel tool for measuring biomechanical properties of human tissues in vivo.

Key Dates

Start date
Aug 19, 2023
Status verified
May 2025
Primary completion
Aug 28, 2026
Completion
Aug 28, 2026

Study Design

Enrollment
90 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Healthy cornea
    Optical imaging of the cornea in healthy subjects
  • Experimental: Healthy skin
    Optical imaging of the skin in healthy subjects
  • Experimental: Healthy gingiva
    Optical imaging of the gingiva in healthy subjects
  • Experimental: Keratoconus cornea
    Optical imaging of the cornea in mild and moderate keratoconus

Primary Outcome Measure

Number of subjects to successfully complete OCT Vibrography without serious unanticipated adverse events related to application of the device. [ Time Frame: 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Massachusetts General HospitalBostonMassachusetts02114
Jing Zhang, PhD
[email protected]
617-373-0127
Seok-Hyun Yun, PhD
[email protected]
6177688704
Seok-Hyun Yun, PhD (SUB_INVESTIGATOR)

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By research site
Massachusetts General Hospital· Boston, MA

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