Cardiovascular Effects of Very Low Nicotine Content Cigarettes

Part of paid clinical trials in Winston-Salem, North Carolina.

Sponsor
Wake Forest University Health Sciences
Study ID
NCT05707871
Phase
EARLY_PHASE1
Status
Recruiting
Apply to this trial

Conditions

  • Tobacco Use

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • SPECTRUM cigarettes — DRUG
    SPECTRUM cigarettes have varying amount of nicotine content
  • usual brand of Cigarettes — OTHER
    Usual Brand of Cigarettes

Study Details

The study is measuring Cardiovascular effects of very low nicotine content cigarettes on daily and non-daily smokers

Key Dates

Start date
Apr 4, 2023
Status verified
Sep 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
49 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Active Comparator: Usual Brand of Cigarettes
    Participants will smoke 2-3 cigarettes of their usual brand
  • Experimental: Research Cigarettes (SPECTRUM)
    Participants will smoke 1-2 SPECTRUM cigarettes

Primary Outcome Measure

Change in Heart rate - Very Low Nicotine Content Cigarettes (VLNCC)s - NRC102/103(0.5mg nicotine) [ Time Frame: Hour 1 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Wake Forest University Health SciencesWinston-SalemNorth Carolina27157
Maria Anwar, MS
[email protected]
802-922-3343

Find similar trials in Winston-Salem, NC

By research site
Wake Forest University Health Sciences· Winston-Salem, NC

Related Studies