INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures

Part of paid clinical trials in Lexington, Kentucky.

Sponsor
Zachary Warriner
Study ID
NCT05642026
Phase
PHASE4
Status
Recruiting
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Conditions

  • Rib Fractures

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Ropivacaine — DRUG
    Patients in this group will receive CINB (continuous local intercostal infusion of 0.2% Ropivacaine). A single catheter will be placed for short segment involvement and two catheters will be placed in series for longer segments of involvement. If necessary and as part of standard of care, CINB treatment will continue after patient discharge. The administration of CINB therapy will continue in the same manner as inpatient therapy.
  • Non steroidal anti-inflammatory drug and opioids — DRUG
    Patients in this group receive nonsteroidal and opioid pain medications (intravenous/oral inpatient and oral outpatient) per standard of care.

Study Details

This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple rib fractures. The objective of this study is to analyze the effect of continuous intercostal nerve block (CINB) in the treatment of patients admitted to the adult trauma service with rib fractures. The effectiveness of CINB as adjunctive treatment will be compared to standard medical therapy involving nonsteroidal and intravenous/oral opioid medications.

Key Dates

Start date
Sep 23, 2025
Status verified
Sep 2025
Primary completion
Feb 1, 2027
Completion
Feb 1, 2027

Study Design

Enrollment
180 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: continuous intercostal nerve block (CINB)
    patients admitted to the adult trauma service with rib fractures who are receiving CINB
  • Active Comparator: standard medical care
    patients admitted to the adult trauma service with rib fractures who are receiving standard medical care

Primary Outcome Measure

Length of hospital stay [ Time Frame: 7 days ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of Kentucky Medical CenterLexingtonKentucky40536
Zachary D Warriner, MD
[email protected]
8593238222
zACHARY D WARRINER, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Lexington, KY

By research site
University of Kentucky Medical Center· Lexington, KY

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