Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia

Part of paid clinical trials in Aurora, Colorado.

Sponsor
University of Colorado, Denver
Study ID
NCT05349630
Phase
EARLY_PHASE1
Status
Not Yet Recruiting

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Conditions

  • Hypoxia
  • Right Ventricular Dysfunction

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

  • Ferrous sulfate 325mg — DRUG
    Participants will take one tab of ferrous sulfate 325 mg (equivalent to 65 mg elemental iron) daily for 30 days.

Study Details

The purpose of this study is to determine if taking iron supplement pills improves exercise performance in low-oxygen conditions.

Key Dates

Start date
Mar 31, 2028
Status verified
Apr 2026
Primary completion
Dec 31, 2029
Completion
May 31, 2030

Study Design

Enrollment
5 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION

Arms

  • Placebo Comparator: Healthy individuals - pre-iron
    Five healthy participants will be enrolled. Baseline echocardiography and exercise data prior to oral iron supplementation will be obtained as part of the "parent" study to this study (NCT05272514).
  • Active Comparator: Healthy individuals - post-iron
    The same five healthy participants will complete echocardiography and exercise testing after taking 30 days of oral iron supplementation.

Primary Outcome Measure

Maximum workload [ Time Frame: Up to 1 hour ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Colorado Anschutz Medical CampusAuroraColorado80045
William Cornwell, MD
[email protected]
303-724-2085
Lindsay Forbes, MD
[email protected]
William Cornwell, MD (PRINCIPAL_INVESTIGATOR)
Lindsay Forbes, MD (SUB_INVESTIGATOR)

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By research site
University of Colorado Anschutz Medical Campus· Aurora, CO

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